摘要
目的探讨CT及MRI在前列腺癌 临床分期中的应用价值差异。方法 选 取124例经外科手术病理检查确诊的前列 腺癌患者为研究对象,均予以术前CT及 MRI检查。以术后病理分期结果为“金标 准”,评估CT及MRI分期的符合率差异。 结果 MRI正确诊断A期18例(78.3%),B期 21例(75.0%),C期36例(85.7%),D期27例 (87.1%);CT正确诊断A期10例(43.5%), B期13例(46.4%),C期35例(83.3%),D 期26例(83.9%);两种检查方法在C、D 期诊断准确率对比上均无统计学意义(P >0.05);A、B期时,MRI分期诊断准确 率明显高于CT,差异具有统计学意义(P <0.05)。结论 MRI检查在A、B期前列腺 癌患者的分期准确率较CT检查高,临床可 将该检查方案应用于前列腺癌患者的术前 分期评估工作中,为治疗方案的拟定提供 依据,值得临床推广。
Objective To investigate the differences in the application value of CT and MRI in the clinical staging of prostaticcancer. Methods 124 patients with prostaticcancer comfirmed by surgical and pathological examination who were treated in the hospital during June 2012 to April 2015 were selected as the research objects.All of them received CT and MRI examination before operation. The results of the examinations weredetailedly recorded and analyzed. The results of postoperative pathological staging were taken as the gold standard to evaluate the differences in coincidence rates of CT and MRI staging. Results The results of surgical and pathological staging showed that among the 124 patients with prostaticcancer, there were 23 cases at stage A(18.5%), 28 cases at stage B(22.6%), 42 cases at stage C(33.9%) and 31 cases at stage D(25.0%). Taking the results of surgical and pathological staging as the gold standard, it indicated that there were 18 cases at stage A(78.3%), 21 cases at stage B(75.0%), 36 cases at stage C(85.7%) and 27 cases at stage D(87.1%) correctly diagnosed by MRI. There were 10 cases at stage A(43.5%), 13 cases at stage B(46.4%), 35 cases at stage C(83.3%) and 26 cases at stage D(83.9%)correctly diagnosed by CT. There was no statistical significance in the comparison of accuracy at stage C and D between the two methods(P>0.05). At stage A and B, the diagnostic accuracy of MRI staging was significantly higher than that of CT and the difference was statistically significant (P<0.05). Conclusion The staging accuracy of MRI examination in patients with prostaticcancer at stage A and B was higher than that of CT, which can be used in the preoperative staging evaluation of patients with prostatic cancer and provide basis for making treatment plan. It is worthy of promotion.
【关键词】前列腺癌;临床分期;CT; MRI
【中图分类号】R445.2;R736.8
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2015.12.033
前言
据不完全资料统计,前列腺癌在我国发比率呈逐年递增趋势[1], 55岁以上的中老年人群为主要发病群体,于70~80岁时患病率达到顶 峰[2]。相关研究证实,该疾病的发生同遗传、种族、饮食习惯、性活 动、代谢异常等因素相关[3-4],病情发展初期可予以根治性治疗方法, 患者生存率较高,中晚期治疗难度大且致死率高,于患者生命健康威 胁较大。如何提高前列腺癌早期诊断及分期准确度,为后续诊疗工作 的顺利开展提供条件也成为各学者探究的热点话题。本次研究以此为 方向,选取124例经外科手术病理检查确诊的前列腺癌患者为研究对 象,以探讨CT及MRI在前列腺癌临床分期中的应用价值差异,现报告如 下。
中国CT和MRI杂志
第13卷, 第 12 期
2015年12月
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