论著-头颈部
百草枯中毒肺损伤CT表现及预后分析
作者:赵 义1,2 许 铁3
所属单位:1.徐州医学院(江苏 徐州 221005) 2.江苏省徐州市第三人民医院中毒职业病科(江苏 徐州 221005) 3.徐州医学院附属医院急救中心(江苏 徐州 221006)
PDF摘要
目的探讨百草枯中毒肺损伤CT 表现以及预后分析,为临床治疗提供诊疗 基础。方法 选取我院急诊科已确诊为百 草枯中毒患者48例,分析其中毒肺损害的 CT表现,对其影像进行评估。结果 CT结 果显示患者肺纹理增多、肺膜玻璃样病 变、肺部实质性病变、肺间质性病变、支 气管扩张等症状。中毒7日内,48例百草 枯患者死亡共9例,其余患者均有不同程 度病变;中毒8~14日内,余下39例百草枯 患者死亡共5例,其余患者病变症状较7日 加剧;中毒15日后,余下34例百草枯患者 死亡共4例,其余患者CT表现症状均有所 缓解。结论 百草枯中毒肺损伤CT表现与 临床病情发展呈正相关,为治疗以及提供 诊断基础,适宜临床应用推广。
Objective To investigate the CT manifestations and prognosis of paraquat poisoning lung injury. Methods 48 paraquat poisoning patients from our hospital were selected and the CT features of lung injury were analyzed. Results CT results showed that patients with lung increased, lung membrane lesions, pulmonary parenchymal lesions, pulmonary interstitial lung disease, bronchial dilatation and other symptoms. In 7 days after poisoning, 48 patients died in 9 patients, and the remaining patients had different degrees of disease. In 8-14 days, the remaining 39 cases of paraquat patients died of a total of 5 cases, the rest of the patients had more progressive symptoms than those of 7 days. 15 days after poisoning, the remaining 34 patients died in 4 patients, the rest of the patients with CT symptoms were relieved. Conclusion The CT manifestations of lung injury induced by paraquat poisoning were positively correlated with the development of clinical disease, which was suitable for clinical application.
【关键词】百草枯;中毒;肺损伤;CT表现;预后
【中图分类号】R595.4; R563.8; R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.12.005
前言
百草枯具有严重毒性作用,若人类服用,致残率极高,其死亡率 高达93%[1]。如果误食或药物服用过量,最为明显的损伤部位是肺脏, 发病机制为肺部产生的超氧离子过多,引起肺部受损[2]。因此其早期 诊疗尤为关键。临床应用最为广泛的诊断方式为CT[3]。临床尚无治疗 百草枯的特效药,而常见治疗方法为对症治疗,患者治愈率低,疗效 不佳。因此,本研究进行临床研究分析,探讨百草枯中毒肺损伤CT表 现分析,为百草枯诊疗以及预后提供临床理论依据。
中国CT和MRI杂志
第13卷, 第 12 期
2015年12月
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