摘要
目的探析18F-FDG PET/CT显像在 胃癌患者治疗后随访中的应用价值。方法 选择我院2011年4月-2013年4月收治52例 胃癌患者作为研究对象,行PET-CT扫描, 比较18F-FDG PET/CT显像与平扫CT的随访 诊断准确率。结果 52例胃癌患者中共24 例出现复发及转移(20例为远处转移、4 例为原位复发)。18F-FDG PET/CT的复发及 转移诊断准确率达87.5%,明显高于平扫 CT的58.3%,差异的比较有统计学意义(P <0.05)。结论 18F-FDG PET-CT显像在胃 癌患者治疗后随访的应用可根据肿瘤组织 代谢情况有效诊断复发与转移情况,作为 进一步治疗的依据,具有显著临床价值。
Objective To analyze the 18F-FDG PET/CT imaging application value in patients with gastric cancer after treatment follow-up. Methods A total of 52 cases of gastric cancer patients from April 2011 to April 2013 were selected as the research object, and compare the follow-up diagnostic accuracy of CT and 18F-FDG PET/CT imaging. Results There were 24 cases of gastric cancer recurrence and metastasis (20 cases of distant metastasis, 4 cases of recurrence in situ). The diagnosis accuracy rate of recurrence and metastasis by 18F-FDG PET/CT was 87.5%, significantly higher than 58.3% of CT, the difference was statistically significant(P<0.05). Conclusion 18F-FDG PET/CT imaging in patients with gastric cancer follow-up can be effectively reflected the recurrence and metastasis and could be the basis for the further treatment, which has significant application value.
【关键词】PET-CT;18F-FDG;胃癌;糖代谢
【中图分类号】R73;R44
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2015.12.026
前言
胃癌为常见恶性肿瘤,以手术切除作为主要治疗手段,但大量临 床研究显示,胃癌术后易出现复发与转移,发生率分别在22%~48% 及20%~40%之间[1-3],而常规影像学检查方法无法准确鉴别肿瘤复发 与术后纤维化。正电子发射断层显像(positron emission tomography,PET)为功能显像技术,同时结合了CT解剖影像及PET功能影像[4], 可通过一次性成像获得两者融合信息,利于早期发现胃癌转移及复 发,且在病灶的探测、定性、定位方面具有重要作用,可作为再次 手术与进一步治疗的依据。本文以我院收治胃癌患者为例,探析18FFDGPET/CT显像在胃癌患者治疗后随访中的应用价值,报道如下。
中国CT和MRI杂志
第13卷, 第 12 期
2015年12月
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