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颅内静脉窦血栓患者30例的临床特点及影像学表现分析

作者:隋海晶1 赵振国1 白青科2 谢秀海1

所属单位:1.上海市浦东新区人民医院放射科(上海 201299) 2.上海市浦东新区人民医院神经内科(上海 201299)

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摘要

目的探讨颅内静脉窦血栓患者 30例的临床特点及影像学表现。方法 回 顾性分析30例诊断为颅内窦静脉血栓患者 的临床特点及影像学表现。结果 本组30 例患者中,31-50岁CVST发病率最高;病 因以妊娠相关因素最为常见,占23.33%; 30例均行头颅CT平扫,显示16例存在异 常,其中3例出现弥漫性脑水肿,存在空 三角征;5例脑实质低密度影;2例病变 静脉窦内出现高密度影;27例行MRI扫描 结果显示,22例脑内信号异常,其中8例 为单侧病灶,14例为双侧病灶。26例MRV 检查显示存在不同程度的窦静脉病变,主 要表现为受累窦静脉不显影或显影不清。 DSA检查结果显示存在不同程度的窦静脉 堵塞。结论 CVST的病因较为复杂,临床 症状表现不一,疑似CVST患者应及时行 CT、MRI及MRV等影像学检查,进行疾病确 诊,并早期给予个性化治疗,能够改善疾 病预后。

Objective To investigate the clinical features and imaging findings of 30 cases of patients with intracranial venous sinus thrombosis, and to improve the understanding of the disease. Methods The clinical features and imaging findings of 30 patients with intracranial venous sinus thrombosis were retrospectively analyzed. Results Among the 30 patients, the morbidity of CVST in 31-50 year-old patients was the highest,. The 30 cases were given CT scan, which showed that there was abnormity in 16 cases, including 3 cases of diffuse brain edema, with empty triangle sign, 5 cases of brain parenchyma low- density shadow; 2 cases with high-density shadow in the diseased venous sinus. MRI scan was performed in 27 cases, which showed that there were 22 cases of abnormal brain signal, including 8 cases of unilateral lesions and 14 cases of bilateral lesions. The main features were cerebral infarction and cerebral edema. 26 cases of MRV examination showed that there were different degrees of sinus venous diseases and the main performance was affected sinus venous not developing or not clearly developing. DSA examination showed that there were different degrees of sinus venous congestion. Conclusion The cause of CVST is complex and the clinical symptoms are different. Patients with suspected CVST should receive CT, MRI, MRV and other imaging examinations to diagnose the disease, and to receive early individualized treatment, which can improve the prognosis of the disease.

【关键词】颅内静脉窦血栓形成;临床特点;CT;磁共振成像;核磁共振静脉成像

【中图分类号】R445.2;R445.3

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.12.013

前言

颅内静脉窦血栓形成(CVST)是由多种原因诱发的脑静脉回流受阻 的脑血管疾病,年发病率为5/100万,占卒中发病率的0.5%左右[1]。 CVST的预后较差,死亡率高达30%~50%,直接影响着患者预后生存 质量。近年来,随着影像学技术在临床的应用,如CT、磁共振成像 (MRI)、核磁共振静脉成像(MRV)等,提高了CVST的诊断准确率,对临 床早期干预治疗具有重要意义。本文总结30例CVSE患者的临床特点、 影像学表现,旨在提高临床对疾病的认识,现报道如下。