目的探讨CT、MRI在诊断原发性 中枢神经系统淋巴瘤(primary central nervous system lym phoma，PCNSL)以及 PCNSL的CT和MRI影像学特点。方法 选择 经我院病理及临床证实为PCNSL的患者78 例为研究对象，所有患者均行多层螺旋CT 及MRI平扫和增强扫描，观察淋巴瘤的CT 和MRI影像特点，对肿瘤实质区、瘤周水 肿区的1 H-MRS及ADC值与健侧区比较。结 果 CT、MRI显示，PCNSL病变的好发部位 包括额叶、顶叶及基底节区；PCNSL的CT 影像主要表现为等或略高密度，MRI影像 主要表现为等或略长T1、等或略长T2信 号，DWI呈等高、略高或高信号，肿瘤实 质均呈明显强化；肿瘤实质区Cho/NAA、 Cho/Cr、Lip/Cr明显高于瘤周水肿区和健 侧对照区，NAA/Cr和ADC明显低于瘤周水 肿区和健侧对照区(P＜0.05)。结论 在 PCNSL的诊断中，多层螺旋CT、MRI均具有 较高的价值，可清晰显示肿瘤形态、密度 及代谢情况，而MRI的诊断价值更高。

Objective To explore the CT and MRI in the diagnosis of primary central nervous system lymphoma (PCNSL) and the CT and MRI imaging characteristics of PCNSL. Methods Select confirmed by our hospital pathology and clinical 78 cases of PCNSL patients as the research object, all the patients were row multislice CT and MRI scan and enhanced scan, observation of CT and MRI imaging characteristics of lymphoma, the tumor nature, tumor weeks edema area to 1H-MRS and ADC values compared with the contralateral area. Results CT and MRI showed that PCNSL lesions of good hair parts including the frontal, parietal lobe and basal ganglia region; PCNSL CT images mainly for or slightly high density, such as MRI image is mainly or slightly long T1, or slightly long T2 signals, such as DWI is high, can slightly higher or high signal, tumors are in obvious strengthening the essence; Tumor parenchyma area Cho/NAA, Cho/Cr, Lip/ Cr significantly higher than the tumor weeks edema zone and the contralateral control area, NAA/Cr and ADC significantly lower than the tumor weeks edema area and the contralateral control area (P<0.05). Conclusion In the diagnosis of PCNSL, MDCT, MRI has high value, can be clearly shows that the tumor shape, density and metabolism, and the diagnostic value of MRI is higher.