论著-头颈部
小脑血管母细胞瘤MR表现及病理分析
作者:孙献勇1 鲁珊珊2 张永娣1 时维东1
所属单位:1.解放军第149医院放射科(江苏 连云港 222042) 2.南京医科大学第一附属医院放射科(江苏 南京 210029)
PDF摘要
目的探讨小脑血管母细胞瘤的 MR影像表现与病理特点,以提高术前诊 断准确率。方法 回顾性分析经手术病理 证实的22例小脑血管母细胞瘤,全部患 者均行MR平扫及增强扫描。结果 单发21 例,多发1例,所有病灶均位于小脑内。 21例单发病例中,MR表现大囊小结节型17 例,实质型2例,单纯囊型2例。肿瘤的囊 液部分显示为长T1长T2信号,T2-FLAIR为 稍低、等或稍高信号;实性部分或瘤结 节呈稍长T1稍长T2信号,增强后明显强化。 SWI序列可见到瘤内或瘤周的异常扭曲血 管影。1例多发病例表现为1个大囊小结节 型及2个小结节状实质型病灶。病理组织 学检查肿瘤主要由两种成分构成:不同成 熟阶段的毛细血管和毛细血管网之间丰富 的间质细胞。结论 小脑血管母细胞瘤具 有典型的MR表现,且与其病理基础密切相 关。MR是诊断小脑血管母细胞瘤的有效检 查方法。
Objective To analyze the MR feature and pathological findings of the cerebellar hemangioblastomas so as to raise the diagnostic accuracy. Methods MR imaging and pathological features of the cerebellar hemangioblastomas in 22 cases were analyzed retrospectively. All of the patients underwent routine enhanced MR scan. Results There were 21 cases with solitary tumor and 1 case multiple tumors. A total of 22 hemangioblastomas were located intracerebellar.Among 21 solitary cases, 17 cases were large cystic with small nodule type, 2 cases were solid mass type, and 2 cases were purely cystic type. The cystic liquid exhibited the long T1 and T2 signal and nearly isointense on T2-FLAIR. The solid part or nodule showed slightly low signal on T1WI, slightly high signal intensity on T2WI and could be significantly enhanced. It could be appeared distortion abnormal blood vessel within and around the tumor on SWI. 1 case multiple tumors included 1 large cystic with small nodule and 2 small solid nodules type. Histopathologically, this tumor was characterized by two main components: capillary and stromal cells. Conclusion The MR findings of the cerebellar hemangioblastoma has certain features, which are closely related to its pathology. MR is the effective inspection method for cerebellar hemangioblastoma.
【关键词】小脑;血管母细胞瘤;磁共振成像;病理学
【中图分类号】R739.41; R445.2
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.07.005
前言
小脑血管母细胞瘤(Hemangioblastoma,HB)又称血管网状细胞 瘤、血管网织细胞瘤,是一种少见的血供丰富的良性肿瘤,好发于成 年人,占颅内肿瘤的2%,占成人后颅窝肿瘤的7~10%,其中囊性多发 生于小脑半球,实质性多发生于脑干、小脑蚓部及脊髓等位置[1-2]。本 文回顾性分析经手术病理证实的22例小脑HB,探讨其MR表现与病理特 点。
中国CT和MRI杂志
第13卷, 第 7 期
2015年07月
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