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MRI测量股骨头坏死塌陷前期髋关节软骨的厚度及表观弥散系数分析*

作者:冷晓明 姜胜攀 黄 勇 曾道辉 冯 欣 赵 曼 王晓春

所属单位:广州中医药大学第一附属医院(广东 广州 510405)

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摘要

目的分析MRI测量股骨头坏死塌 陷前期髋关节软骨的厚度及表观弥散系 数。方法 随机选取医院收治的2013年1月 到2015年1月60例经影像学检查诊断为股 骨头坏死塌陷前期的患者,并且将其作为 研究组(60例);同时,选择同期60例行盆 腔扫描的无髋关节症状的非股骨头坏死的 成年人,将其作为对照组(60例);针对临 床两组进行MRI测量,分析股骨头坏死塌 陷前期患者髋关节软骨厚度以及其表观弥 散系数(ADC),为预测股骨头塌陷提高观 察指标。结果 对两组进行MRI测量发现, 在股骨头坏死塌陷前期,对照组成年人髋 关节软骨ADC均值为(10.89±1.66)×10-5 mm2 /s,软骨厚度为1.9mm;研究组髋关节 软骨ADC均值为(15.23±4.72)×10-5mm2 / s,塌陷前期髋关节软骨厚度为1.2mm, 两组软骨厚度以及表观弥散系数存在差 异,研究组与对照组比较具有统计意义 (P<0.05)。结论 在临床股骨头坏死诊断 中,应用MRI测量髋关节软骨的厚度、表 观弥散系数,对关节软骨反应灵敏,可以 有效预测早期股骨头坏死塌陷,为临床软 骨病变诊断提供参考标准。

Objective To analysis the MRI measured pre collapse osteonecrosis of the hip cartilage thickness and apparent diffusion coefficient. Methods 60 cases of hospital from 2013 January to 2015 1 menstrual imaging diagnosis for early avascular necrosis of femoral collapse in patients, as well as the study group (60 cases); at the same time, 60 cases of pelvic scan without hip symptoms non avascular necrosis of the femoral head in adults, as the control group (60 cases); MRI measurement for the two clinical groups avascular necrosis of the femoral head collapse, in patients with hip cartilage thickness and the apparent diffusion coefficient (ADC), for the prediction of femoral head collapse to improve the observation index. Results two groups of MRI measurement, in avascular necrosis of the femoral head collapse early in the study group, the control group of normal adult articular cartilage mean ADC (10.89±1.66)×10-5mm2 /s, the thickness of articular cartilage; articular cartilage of group mean ADC (15.23±4.72)×10-5mm2 /s, stage of hip the thickness of articular cartilage was 1.2mm, two groups of cartilage thickness and apparent diffusion coefficient are different, the study group compared with the control group, with statistical significance (P<0.05). Conclusion In the clinical diagnosis of femoral head necrosis, measurement of articular cartilage using MRI thickness, apparent diffusion coefficient, on articular cartilage of sensitive reaction, can effectively predict the early avascular necrosis of the femoral head collapse, and provide reference standard for clinical diagnosis of articular cartilage lesions.

【关键词】股骨头坏死;MRI;软骨厚度;髋关节软骨、表观弥散系数

【中图分类号】R322.7+2

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.07.031

前言

股骨头坏死(Osteonecrosis of the Femoral Head,ONFH)作为一 种髋关节疾病,临床残疾率极高[1],其发病病因多是由于股骨头血液 供应不足而产生血循环障碍造成的,极易导致股骨头坏死塌陷,造成 股骨头发生不可逆性改变[2]。临床采取MRI测量手段,精确预测股骨头 坏死发生塌陷的风险,对于临床早发现早治疗发挥一定的作用[4]。本 研究对近年医院收治60例股骨头坏死塌陷前期患者,对其临床资料进 行统计分析,分析MRI测量股骨头坏死塌陷前期髋关节软骨的厚度及表 观弥散系数改变,为临床预测股骨头坏死塌陷提供方案。