目的探讨肝内周围型胆管 细胞癌 ( I n t r a h e p a t i c p e r i p h e r a l cholangiocarcinoma,IHPCC)的MSCT表现 及肿瘤标志物CA199与IHPCC的相关性， 提高对IHPCC的认识。方法 收集自2009 年1月至今我院肝胆外科经手术术后病理 确诊的IHPCC患者30例，肝良性病变(肝 囊肿，肝内胆管结石等)30例。回顾性分 析所有患者的MSCT诊断结果及CA199检测 结果，综合评价MSCT与CA199在单独或联 合诊断IHPCC中的应用效果。结果 MSCT 诊断IHPCC的准确率为92.00%，特异度 为80.00%；CA199诊断IHPCC的准确率为 72.41%，特异度为69.70%；两种计数联合 应用诊断IHPCC的准确率为100%，特异度 为95.45%。结论 MSCT结合CA199联合检 测，可显著增强对IHPCC患者的术前诊断 水平。对于提取制定手术方式，指导术中 及术后早期治疗具有重要指导意义。

Objective To investigate the MSCT features of intrahepatic peripheral cholangiocarcinoma(IHPCC) and the correlation of tumor markers CA199 and IHPCC , improving the understanding of IHPCC. Methods From January 2009 to now, 30 patients with IHPCC（diagnosed by pathological examination）and 30 patients with liver benign lesion were studied. Retrospective analysis was applied for all the data including the results of MSCT and CA199. Comprehensive assessments were used to study the diagnose effect of united use of MSCT and CA199. Results For the diagnosis of IHPCC, accuray of MSCT alone was 92.00% while sensitivity 80.00%. As to CA199, the accuracy was 72.41% while sensitivity was 69.70%. When both indexes were used, the accuracy was 100% and sensitivity was 95.45%. Conclusion The combination of MSCT and CA199 significantly increased the accuracy and sensitivity of IHPCC before the surgery was done. This combination is of great importance for helping the surgeons in making surgery strategies and peri-operative therapy plans.