论著-头颈部
低剂量64层螺旋CT双动脉期多期扫描与超声造影诊断小肝癌随机对照分析*
作者:梁 韬 易旦冰 丁建林 梁立华 陈耀强
所属单位:深圳市福田区人民医院影像科(广东 深圳 518033)
PDF摘要
目的研究低剂量64层螺旋CT 扫描和超声造影诊断对小肝癌 ( S m a l l hepatic carcinoma,SHCC)的临床诊断价 值。方法 研究年限为2012年12月-2014 年12月,对象为38例经门诊和住院部收 治的超声检查提示为肝脏发生占位性病 变的患者,所有患者均接受超声造影检 查(A组)、低剂量64层螺旋CT双动脉期 多期扫描(B组)和两种联合检查(C组)。 对三组患者的诊断结果进行对照。结 果 A组检查的灵敏性(81.85%)、特异性 (78.95%)、准确率(76.32%);B组检查的 灵敏性(78.95%)、特异性(84.21%)、准 确率(73.68%);组间比较*P、**P、#P均 >0.05,无显著差异。C组检查的灵敏性 (98.24%)、特异性(100.00%)、准确率 (94.74%);分别与A组和B组比较,*P、 **P、#P<0.05,统计学差异显著。B组检 查中SHCC病灶主要表现为典型的“快进快 出”强化征象,误诊率为2.63%。A组检查 中误诊率为5.26%。结论 64层螺旋CT双动 脉期多期扫描联合超声造影对SHCC的诊断 均具有较高的准确率、灵敏性和特异性, 其能够对缺乏血供、不典型的SHCC肝癌进 行准确诊断,建议在临床诊断中优先选择 使用。
Objective This paper is to investigate clinical diagnosis value of low dose of 64–slice spiral CT scanning and contrast-enhanced ultrasonically in the diagnosis of Small hepatic carcinoma. Methods The years of research extended from December, 2012 to December, 2014, and research subjects were 38 patients admitted by the outpatient clinic and the inpatient department were indicated to suffer from liver space-occupying lesions via ultrasonic examination, 19 patients in the control group were subject to low dose of 64-slice spiral CT multi-phase scanning, and 19 patients in the experiment group were subject to contrast-enhanced ultrasonically. Diagnosis results of patients in two groups were compared on the basis of clinically pathological diagnosis. Results The sensitivity (100.00%) and accuracy (94.74%) of CT examination were higher than those of ultrasound examination (96.63% and 94.44%), but the specificity (98.24%) of CT examination was lower than that of ultrasound examination (100.00%).The intergroup comparison satisfied P>0.05,and there is no significant difference. Medium and small unicellular carcinoma lesions in CT examination mainly manifested enhanced sign of typical "Fast-out and Fast-in" with misdiagnosis rate ar 5.26%. Conclusion Diagnosis of 64 slice spiral CT scan combined with double arterial phase of contrast-enhanced ultrasound on SHCC has higher accuracy, sensitivity and specificity, which can lack of blood supply, not the typical SHCC unicellular carcinoma by accurate diagnosis, to recommend the preferred option for use in clinical diagnosis.
【关键词】低剂量;螺旋CT;超声造影; SHCC
【中图分类号】R735.7
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.07.020
前言
SHCC是肝癌进展期的早期主要病理改变,主要是指单个的癌结节 最大直径≤3cm;癌结节数目不超过两个,其最大直径总和应≤3cm。 SHCC术前准确的影像学诊断有利于对病情的确诊,有助术中对肿瘤的 完全清扫,延长患者的生存期限[1]。CT与超声均为临床常用的传统腹 部影像学检查方式,随着技术的改进和进步,低剂量CT及超声造影也 不断的运用在鉴别诊断肝脏小结节病变中[2]。笔者对近两年本院收治 的38例经超声检查提示为肝脏发生占位性病变的患者采用超声造影及 CT双动脉期多期扫描的检查方式进行诊断,对其诊断结果进行对比研 究分析,从而提高CT及超声造影对SHCC的鉴别诊断能力。
中国CT和MRI杂志
第13卷, 第 7 期
2015年07月
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