摘要
目的通过比较与分析CT脑灌注 (CTPI)与血管造影(CTA)用于临床急性缺 血性脑卒中诊断价值,从而可为临床急 性缺血性脑卒中患者诊断与治疗提供参 考。方法 选取本院58例急性缺血性脑卒 中患者作为本次研究对象,采用CT对患 者进行头颈部CTPI、CTA检查。统计两组 诊断情况,并加以比较与分析。结果 经 检查发现,CT灌注图中,其中与患者临 床症状相对应的灌注异常处共为50例, 阳性率为86.2%明显高于CT检查16例,阳 性率27.6%,P<0.05。灌注异常区CBV和 CBF及MTT参数值与临床镜像健侧比较, P<0.05;经CTA检查发现,患者共存在10 处单纯颈内动脉狭窄、20处单纯颅内动 脉狭窄、8例颈内动脉且颅内动脉狭窄。 联合CTA与CTPI检查发现,责任血管者采 用CTPI检查阳性者38例,阳性率为65.5% 明显高于无责任血管者12例,占20.7%, P<0.05。结论 临床应用CT脑灌注与血管 造影可较好地诊断急性缺血性脑卒中,从 而为临床诊断、预防及治疗提供重要参考 价值。
Objective By comparison and analysis of brain perfusion CT (CTPI) and angiography (CTA) for the diagnosis of acute ischemic stroke clinical value, which can provide a reference for clinical diagnosis of acute ischemic stroke patients and treatment. Methods Select the hospital 58 cases of acute ischemic stroke patients as this study, the use of CT in patients with head and neck CTPI, CTA examination. Statistics groups of diagnosis, and compared and analyzed. Results The inspection found, CT perfusion figure, which corresponds with the clinical symptoms of perfusion abnormalities at a total of 50 cases, the positive rate of 86.2% was significantly higher than that of CT examination in 16 cases, the positive rate of 27.6%, P<0.05. Perfusion abnormalities area CBV and CBF and MTT compare parameter values and clinical mirrored contralateral, P<0.05; by CTA examination revealed that the patient simply co-exist within the 10 carotid stenosis, 20 intracranial arterial stenosis alone, eight cases of internal carotid artery and intracranial arterial stenosis. CTA and CTPI joint inspection found offending vessels were using CTPI test positive in 38 cases, the positive rate of 65.5% was significantly higher than those without offending vessels were 12 cases, accounting for 20.7%, P <0.05. Conclusion The clinical application of CT brain perfusion and angiography may be better diagnosis of acute ischemic stroke, which is a clinical diagnosis, prevention and treatment provide important reference value.
【关键词】CT脑灌注;血管造影;急性缺 血性脑卒中;诊断
【中图分类号】R743.3;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2015.07.002
前言
急性缺血性脑卒中是一种常见性的脑血管疾病,严重威胁人们生 命健康。这种疾病发病原因主要为动脉栓塞和动脉粥样硬化,该疾病 具有较高死亡率及残疾率,幸存者大多存在不同程度神经功能障碍, 严重影响其日常生活质量[1]。待患者发生缺血性脑卒中后,其脑组织 初选缺血、缺氧等症状,从而致使其神经细胞死亡,而此过程为不可 逆过程,因此临床治疗主要是促进患者血流再通,及时挽救未死亡神 经细胞,从而改善其预后。所以,临床及时诊断及预防、治疗对该疾 病具有重要意义,近年来,随着临床医学技术及医疗设备不断进步, 采用CT和MRI及血管造影均可较好地显示患者脑动脉或脑组织内器质性 病变发生,同时还可定量测量,从而具有较高准确性[2]。采用CTPI检 查可有效反映出患者组织内血流动力学变化,同时还可于形态学变化 前预示病变发生,具有较高应用价值[3]。然CTA可及时而准确诊断颈动 脉狭窄。本次研究为探讨CTA与CTPI应用于临床急性缺血性脑卒中诊断 价值,从而为临床患者规范化诊断及治疗提供参考,如下。
中国CT和MRI杂志
第13卷, 第 7 期
2015年07月
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