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Flash CT扫描对 OSAS患者的动态成 像及辐射剂量研究*

作者:何桂茹1 杨进军1 刘 艳1 古丽巴哈2 杨 君1 李江红1

所属单位:1.新疆医科大学第五附属医院CT室 2.新疆医科大学口腔颌面外科(新疆 乌鲁木齐 830000)

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摘要

目的探讨Flash CT在阻塞性睡 眠呼吸暂停综合征(OSAS)诊断中的应用价 值。方法 A组:11例OSAS患者在睡眠前、 后分别进行大螺距Flash CT扫描,然后 进行气道三维重建,多层面重建(MPR),容 积显示(VR)进行观察,测量上气道的矢状 径、冠状径及截面积;B组:常规MSCT扫 描OSAS患者11例,分析比较两组病例的辐 射剂量。结果 OSAS患者睡眠呼吸暂停时 气道最狭窄处面积比清醒时明显变小,在 悬雍垂区差异有统计学意义(P<0.05)。 A组有效辐射剂量ED(0.43±0.019)msv, B组为(0.76±0.033)msv,A组比B组减少 了43.43%的有效辐射剂量,有统计学差异 (P<0.05)。结论 双源CT flash扫描可动 态观察气道,并对狭窄部位和范围进行定 位,为选择治疗方案包括外科手术方式提 供可靠依据,并可降低辐射剂量。

Objective To asses the application value of flash CT amomg the patients with obstructive sleep apnea syndrome (OSAS). Methods 11 patients with OSAS were scanned by high-pitch spiral scanning in sleeping and nonsleeping status respectively ,and upper airway were reconstruct in group A,and the cross-section area with its corresponding sagital,axial,cornal diameters were mesureed respectively. In MSCT scanning mode were applied in group B.The CT dose (ED) were compared between two groups. Results OSAS patients were obviously smaller in sleeping status than in nonsleeping status .There are statistically significant difference at the uvula levels (P<0.05).The ED in group A and B was (0.43±0.019) msv and (0.76±0.033) msv(P<0.05).The effective dose was decreased by 43.43% for group A. Conclusion Flash CT helps evaluating the degree and range of stenois of the upper airway in OSAS patients and is useful in treatment planning. The diagnosis of OSAS disease using flash scan mode can reduce radiation expose than using MSCT scanning mode.

【关键词】睡眠呼吸暂停综合征;双源CT; 大螺距;动态成像;低剂量

【中图分类号】R445.3

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.03.33

前言

双源flash CT机与常规螺旋CT比较,螺距更大,可以达到更快的 扫描速度,在很短的时间内(1秒内)采集完目标部位,甚至可以在一个 心动周期内完成整个图像的采集。阻塞性睡眠呼吸暂停综合症(OSAS) 病人是睡眠时发生呼吸紊乱,其上气道在睡眠时反复出现完全或部分 塌陷,但患者的CT检查多在清醒时扫描。OSAS患者在清醒状态下与睡 眠后发生暂停时气道变化是否一致,病变的程度如何,扫描的方法及 所受辐射剂量在临床上尚未引起重视。本研究将观察OSAS患者的上气 道,分别在清醒时和睡眠呼吸暂停进行扫描,揭示其动态变化。OSAS 患者CT检查具有多种不同扫描模式,本研究即评价其大螺距Flash模式 与常规螺旋扫描(MSCT)的辐射剂量的差别。