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磁共振扩散加权成像在卵巢囊腺癌与囊腺瘤鉴别诊断中的价值

作者:梁长松 陈 忠 李伟峰

所属单位:广东省江门市新会区人民医院影像中心(广东 江门 529100)

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摘要

目的探讨MR扩散加权成像(DWI) 在卵巢囊腺癌与囊腺瘤鉴别诊断中的价 值。方法 回顾性分析经临床手术及病理 证实的28例卵巢囊腺癌及30例卵巢囊腺瘤 患者MR图像,记录两者囊壁或间隔DWI信 号高低并测量其ADC值(b=800s/mm2 ),并 进行统计学分析。结果 28例卵巢囊腺癌 表现为囊实性肿物,囊壁及间隔不规则增 厚,壁结节或实性成分DWI均表现为高信 号(100%),平均ADC值(0.95±0.18)×10- 3 mm2 /s。30例囊腺瘤为单房或多房肿物, 边缘光滑,囊壁及间隔厚度均匀或不均 匀,28例高b值扩散加权成像信号不高 (93.3%),平均ADC值(1.72±0.28)×10- 3 mm2 /s。DWI诊断囊腺癌敏感性高(100%), 特异性高(93.3%)。囊腺癌与囊腺瘤DWI信 号高低、ADC值之间比较差异有统计学意 义(P<0.05)。结论 DWI在囊腺癌与囊腺瘤 鉴别诊断中有重要作用,通过对病变ADC 值进行定量分析,能为卵巢囊腺癌及囊腺 瘤定性诊断提供一定的依据。

Objective To evaluate the value of diffusion weighted imaging in diagnosis of ovarian cystadenocarcinoma. Methods 28 patients with pathologically-proved cystadenocarcinama and 30 patients were cystadenoma based on MR imaging were retrospectively analyzed, record the DWI signal of the cystic wall or interval and measuring its ADC value (b=800s/mm2 ) and nonparametric test was used. Results The MR findings of cystadenocarcinoma were complex solid and cystic ovarian tumors with thick,irregular wall with thick sepa,mural nodule,and soft tissue component,which showed hyperintensity on DWI,and the mean ADC values was (0.95±0.18)×10- 3 mm2 /s. The cystadenoma findings were thin and smooth wall with uniocular or multicular,lacks of the mural nodule, which showed hypointensity on DWI,and the mean ADC values was (1.72±0.28)×10-3mm2 /s.In diagnosis of cystadenocarcinoma on DWI provided sensitivity 100% and specificity 93.3%,the DWI signal and the ADC value in comparison wih cystadenocarcinoma and cystadenoma have statistical differences(P<0.05). Conclusion DWI sequence play an important role in diagnosis of cystadenocarcinoma and cystadenoma,by analysis of the ADC values we found that the ADC values can provide qualitation value,and have differential value in diagnosis of cystadenocarcinoma and cystadenoma.

【关键词】卵巢肿瘤;囊腺癌;磁共振成像;扩散加权成像

【中图分类号】R737.31

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.03.25

前言

妇产科中最常见的手术是卵巢肿瘤切除术,随着患者对术后生活 质量要求的逐步提高,腹腔镜在妇产科的应用逐步增加,因此术前评 估肿瘤的良恶性显得尤其重要,影像学对肿瘤的良恶性诊断是妇科施 行术式的一个重要参考依据。卵巢囊腺瘤(cystadenoma)与卵巢囊腺 癌(cystadenocarcinoma)是妇科最常见的良、恶性上皮肿瘤,B超及CT 对两者鉴别诊断有一定价值,但良、恶性肿瘤之间表现常有重叠[1,2], 常规MR序列虽然对壁薄、均匀,无壁结节或实性成分的囊腺瘤容易 鉴别,但对对一些厚壁或囊实性肿物不易鉴别良恶性,扩散加权成像 (diffusionweighted imaging,DWI)属功能成像,国外已有学者应用 DWI对卵巢肿物的良恶性鉴别进行研究[3,4],但单独对卵巢囊腺癌及囊 腺瘤的研究较少,本研究应用DWI对厚壁或有壁结节、囊实性卵巢囊腺 癌及囊腺瘤进行研究,旨在探讨DWI对两者的鉴别诊断价值。