目的探讨T2WI结合DWI对低危 (Gleason 评分<6)、中危或高危Gleason 评分≥7前列腺癌诊断价值。方法 51例前 列腺癌患者在前列腺切除术前执行3.0T磁 共振检查。由2名放射医师在T2WI和T2WI 结合ADC图像分析8个区前列腺癌可能。结 果分为低危、中危或高危前列腺癌两组， 及与病理结果相关性。采用ROC进行T2WI 和T2WI结合DWI诊断分析，结果 在2名放 射医师中，T2WI结合DWI对中危或高危前 列腺癌诊断性曲线下面积大于T2WI曲线 下面积(放射医师1：0.887、0.859；放 射医师2：0.732、0.662)，P<0.05，但 T2WI结合DWI对低危前列腺癌诊断性曲线 下面积(放射医师1：0.719、0.725；放射 医师2：0.685、0.680)无统计学意义， P>0.05。2名医师为0.689。结论 DWI结合 T2WI能够增加中危或高危前列腺癌检出 率，但对低危前列腺癌无诊断作用。

Objectives To evaluate the value of diffusion weighted imaging (DWI) in combination with T2-weighted imaging to detect low (Gleason score≤6) and intermediate or high risk (Gleason score≥7) prostate cancer. Methods Fifty-one patients who underwent MRI examinations before prostatectomy were evaluated. Two radiologist independently scored the probability of tumour in eight regions of prostate on T2- weighted images (T2WI) and T2WI combined with apparent diffusion coefficient (ADC) maps. Data were divided into low risk and intermediate or high risk prostate cancer two groups and correlated with histopathological results.Receiver-operating characteristic curve (ROC) was used to diagnose. Results For both readers, ROC of combined T2WI and ADC maps were greater than those of T2WI in intermediate or high risk (radiologist 1: 0.887, 0.859; radiologist 2:0.732 , 0.662,) prostate cancers, P<0.05, but not in low risk (radiologist 1:0.719, 0.725; radiologist 2: 0.685,0.680)prostate cancers, P>0.05. κ value of combined T2WI and ADC maps was 0.689. Conclusions The addition of DWI combined with T2-weighted imaging can improves the accuracy of detecting intermediate or high risk prostate cancers, but not for low risk prostate cancer detection.