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MRI在子宫腺肌症的诊断价值

作者:黄杰灵1 熊伟立1 邓立维1 成官迅2

所属单位:1.南方医科大学第五附属医院(广东 广州 510900) 2.南方医科大学附属南方医院(广东 广州 510515)

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摘要

目的分析子宫腺肌症的MRI表 现,探讨子宫腺肌症的临床症状及MRI表 现与CA125、PRL相关性,提高子宫腺肌 症的诊断正确率。方法 回顾性分析2011 年1月至2014年6月我院62例子宫腺肌症 的MRI及临床资料,其中57例经手术病理 证实,5例通过介入栓塞术后症状缓解。 结果 在62例患者中,弥漫型子宫腺肌症 45例,局限型子宫腺肌症17例。弥漫型表 现为子宫较弥漫性增大,结合带广泛增 厚,与肌层分界不清,呈T2WI稍低信号、 T1WI等信号,其间混杂多发点状高信号, 呈“雪花样”改变;局限型表现为子宫可 局限性增大,相应结合带增厚,与肌层分 界不清,呈T2WI稍低信号、T1W等信号, 信号可均匀或不均匀,不均匀为内多发点 状高信号。主要临床表现依次子宫增大 (55/62,88.7%)、进行性痛经(48/62, 77%)、月经异常(25/62,40%)、下腹痛 (20/62,32%)、不孕(10/62,16%)。子宫 腺肌症患者的CA125、PRL分泌增多。结论 MRI对子宫腺肌症的诊断具有较高临床价 值;子宫腺肌症的MRI表现具有特征性, 且与CA125及PRL存在相关性,有助于子宫 腺肌症诊断及鉴别诊断。

Objective Analysis on the performance of uterine adenomyosis in MRI,Analysis on the clinical symptom of uterine adenomyosis and the relationship between theuterine adenomyosis and CA125,PRL,to improve the diagnostic accuracy of adenomysosis. Methods A retrospective analysis of 62 cases of the patients with uterine adenomyosis between January 2011 and June 2011, including MRI and clinical data,57 cases confirmed by surgery pathology,5 cases through interventional embolization of symptoms after surgery. Results In 62 cases,diffuse uterine adenomyosis 45 cases,linited type of 17 cases of uterine adenomyosis. Diffuse expression is more diffuse enlargement of uterus,belt thickening,and is no clear boundary between muscular layer and slightly low signal in T2WI,T1WI signal,high signal in multiple point,is "snow" change;Limited type of uterine limitations may be enlarged,and the corresponding belt thickening,and is no clear boundary between muscular layer and slightly low signal in T2W,T1W,such as signal,the sigal can be uniform or non-uniform,uneven for multiple point in high signal.Major clinical manifestations in the uterus increases (55/62,88.7%), progressive dysmenorrhea (48/62,77%),menstrual abnormalities(25/62,40%),abdominal pain (20/62,32%) and infertility(10/62,16%).CA125,PRL secretion increased,uterine adenomyosis patients may be associated with the pathogenesis of uterine adenomyosis. Conclusion MRI in the diagnosis of uterine adenomyosis has high clinical value to diagnosis uterine adenomyosis;Preoperative CA125 and elevated PRL helps to imrove the accurate of uterine adenomyosis.

【关键词】子宫腺肌症;磁共振成像;诊断及鉴别诊断;CA125;PRL

【中图分类号】R445.2,R711.71

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2015.03.21

前言

子宫腺肌症(uterine adenomyosis,UAM)是子宫内膜腺体和间 质细胞向肌层良性浸润的激素依赖性疾病。它可引起痛经、月经异 常、不孕等症状,是多发生于生育期妇女的妇科常见病,发病率约 25%~40%,且呈现逐年上升趋势[1,2]。笔者回顾性分析62例经临床病理 证实或介入术后症状缓解的子宫腺肌症的临床及MRI检查资料,以提高 子宫腺肌症的临床及MRI诊断水平。