目的探讨肾嫌色细胞癌的临床 特征、影像表现及鉴别诊断。方法 回顾 性分析16例经病理证实的肾嫌色细胞癌的 临床资料、CT及MRI表现。结果 16例肾嫌 色细胞癌均为单发病灶，右肾9例，左肾 7例。病灶大小约4-14cm不等，类圆形或 浅分叶状14例、“8”字形2例。CT平扫 密度均匀9例，T1WI等或稍低信号，T2WI 等或稍高信号；密度不均7例，T1WI等低 混杂信号，T2WI高低混杂信号，2例见斑 点状、细条状钙化，2例见星状瘢痕，均 未见出血。增强扫描14例边界清晰，13例 呈轻至中度强化，1例明显强化，实质期 高于皮髓质期，均低于肾皮质；2例边界 不清，1例坏死囊变明显，明显不均匀强 化，1例合并肾周炎症，排泄期强化高于 皮髓质期、肾皮质期。结论 肾嫌色细胞 癌临床表现无特异性，影像表现具有一定 特异性，但当肿瘤体积较大，坏死、囊变 较多并合并肾周筋膜炎时，容易误诊。

Objective To explore the clinical features, imaging appearance and differential diagnosis of chromophobe cell renal carcinoma (CCRC). Materials and Methods The clinical datas, CT and MRI manifestations of 16 patients with CCRC confirmed by pathology were reviewed retrospectively. Results 16 cases of CCRC were solitary lesion, 9 cases located in right kidney and 7 in left kidney. The tumors ranged in size from 4 to 14 cm in diameter, with round or shallow lobulation in 14 cases and "8" shape in 2 cases. The density of 9 cases were homogeneous on CT plain scan, iso-/slightly hypo-intensity on T1WI and iso-/slightly hyper-intensity on T2WI; Two cases were inhomogeneous, iso-/hypo-mixed signal on T1WI and hyper-/hypo-mixed signal on T2WI, punctate, small strip calcification in 2 cases, stellate scar in 2 cases and all no hemorrhage. 14 cases with clear boundary, of which 13 showed slight to moderate enhancement and 1 obvious enhancement, parenchymal phase was higher than corticomedullary phase, lower than the renal cortex; 2 cases wih blurry boundary, of which one has obviously cystic necrosis, showed obvious heterogeneous enhancement, the other together with inflammation around the renal, the excretory phase higher than corticomedullary phase and the parenchymal phase. Conclusion The clinical manifestation of CCRC without specificity, imaging performance has certain specificity, but it's easily misdiagnosed when the tumor accompanied by larger volume, more necrosis and cystic fasciitis, with inflammation around the renal.