Objective To discuss the Multislice CT (MSCT) findings and pathologic characteristics of pulmonary sclerosing hemanagioma (PSH), in order to improve the diagnosis ability of PSH. Methods 18 PSH cases confirmed by surgery and histopathology were enrolled from January, 2009 years to June, 2014 years. Retrospective analysis of the clinical manifestation, MSCT features and pathologic characteristics of PSH were performed. Results (1)17 cases had isolated mass, and 1 case had 2 lesions, a total of 19 lesions. Of these lesions, 7 lesions arised from inferior lobe of left lung and 6 lesions arised from middle lobe of right lung, both of these lesions occupied for 68.4%. In addition, 14 (73.7%) and 9 lesions were located in peripheral and central lung, respectively. (2)Of all cases were well-defined. The majority of lesions presented round or oval, except for 2 lesions showed slight lobulation. Spot calcification was found in 2 lesions. (3)Non-uniformity and continuous enhancement was foud in all lesions. Blood vessel marginating sign was found in 12 cases(63.2%), the halo sign was found in 3 cases and the air meniscus sign was found in 2 cases. (4)PSH was composed of hemorrhagic area, papillary area, solid area, sclerotic area with different proportion. Immunohistochemistry study showed TTF(+). Conclusion The imaging features of PSH is characteristic, MSCT is helpful to make accurate diagnosis before operation.