Objective To explore the diagnostic values of magnetic resonance imaging

(MRI) in children with hand-foot-and-mouth disease (HFMD) complicated with

nervous system damage. Methods The clinical data of 186 children with HFMD

complicated with nervous system damage in our hospital from June 2014 to June 2017

were analyzed retrospectively, and the results of MRI examination were analyzed. Results

Among the 186 cases, 121 were MRI positive with the positive rate of 65.05%, and the

total number of lesions was 287. There were 74 cases (61.16%) with multiple lesions, of

which 61 cases (82.43%) were symmetry lesions and 13 cases (17.57%) were asymmetric

lesions. Lesions in MRI showed mainly slightly low signal or low signal in T1WI and

slightly high signal or high signal in T2WI, T2FLAIR and DWI, and there were flaky

and spot-like shadows, fuzzy edge and no mass effect, and some lesions were more clear

in T2FLAIR, DWI sequences. The detection rates of different MRI sequences showed

that T1WI (35.89%)<T2WI (44.95%)<T2FLAIR (77.70%)<DWI (86.06%) (P<0.05).

Conclusion MRI has high diagnostic values for HFMD with nervous system damage, and

T2FLAIR and DWI sequences have high detection rate for lesions and can be used as the

preferred sequences for early detection of children.