Head and Neck Imaging

The Diagnostic Value of Gd-EOB-DTPA in the Diagnosis of Focal Nodular Hyperplasia

Author:ZHANG Jin-yue, WANG Yan

affiliation:Department of Radiology, the Third People's Hospital of Luohe, Luohe 462000, Henan Province, China

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Abstract

Objective To investigate the value of Gd-EOB-DTPA in the Diagnosis of Focal Nodular Hyperplasia (FNH). Methods MRI findings of 14 cases with FNH proved by pathology were analyzed retrospectively. All were performed MRI plain and enhanced with Gd-EOB-DTPA. Results There were 6 cases located at left lobe, 4 cases at right lobe, 2 cases at caudate lobe, 2 cases crossed leaves. MRI findings: 8 cases showed equal signals, 6 cases showed slightly lower signal on T1WI, 5 cases showed equal signals, 9 cases showed slightly higher signal on fat suppression T2WI. 7 cases with central scars could be seen, and showed low signal on T1WI, high signal on T2WI.14 cases all were significantly enhanced, including 4 cases were seen tortuosity strengthened arteries during dynamic contrast-enhanced arterial phase,all continued to strengthen during the portal phase, and 12 cases showed slightly higher signal, 2 cases showed equal signal; during the balance phase, 6 cases showed equal signal, 8 cases showed slightly higher signal. During liver cell specific phase, 7 cases showed equal signals, 7 cases were uneven slightly, equal and slightly lower mixed-signals. 7 cases with central scar and without enhancement during the arterial phase, delay continued to enhance during portal venous phase and balance phase, showed low signal during liver cells specific phase. Conclusion The use of Gd-EOBDTPA-enhanced to diagnose FNH had high sensitivity and specificity, especially during liver cell specific phase, FNH specifically absorbed Gd-EOB-DTPA and showed equal、 high signal. Gd-EOB-DTPA-enhanced MRI could fully and accurately show the blood supply and pathological features of FNH, and greatly improved the ability of differential diagnosis with other hepatic diseases.

【Keyword】Gd-EOB-DTPA; Focal Nodular Hyperplasia; Magnetic Resonance Imaging; Contrast Media

【Chart number】R445.2;R575

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2018.02.002