Objective To evaluate the value of hematoma enlargement rate in the diagnosis of hyperplasia of intracerebral hemorrhage. Methods The images and clinical data of 78 patients with hyperacute cerebral hemorrhage were analyzed retrospectively from June 2016 to July 2017. The ultre-early henmatoma growth (uHG) was calculated, that is, the first CT The ratio of hematoma volume to the time of first CT scan was reviewed. CT was used to evaluate hematoma enlargement. The ROC curve was used to analyze the accuracy of uHG in predicting hematoma enlargement and to determine the threshold of hematoma enlargement. Results Analysis of 78 patients with hyperacute cerebral hemorrhage showed that the rate of superficial hematoma enlargement was faster in patients with hematoma enlargement (P<0.05), and the area under the AUC was 0.880 (95% CI, 0.797-0.963, P<0.001). The sensitivity (81.5%) and specificity (88.2%) were the highest when uHG=7.14ml/h. Conclusion The rapid expansion of hematoma in CT scan is predictive of hematoma enlargement. When hematoma enlargement rate is 7.14ml/h, it can be used as a stratification scheme for predicting the risk of hyperosmolar hematoma enlargement.