Objective Analyze the imaging features of pulmonary benign and malignant solitary ground glass opacity (GGO) in order to improve the diagnostic accuracy of the disease. Methods A retrospective analysis of medical imaging in 56 patients with lung GGO science data and pathological data were conducted during the October 2013- May 2016. Results In 56 patients, the gender ratio, the age, the average cross-sectional size of the lesion, the difference of the lesion distribution was not statistically significant between benign and malignant GGO groups(P>0.05). Malignant GGO more prone to present bronchial truncation sign, lobulation, burr sign, small bubbles, pleural indentation, vascular convergence sign(P<0.05). Differences of CT values in the solid part of lung benign and malignant solid GGO were not statistically significant. Conclusion The malignant probability of partial solid GGO lesions was higher than that of pure GGO. When the lung GGO lesions presented bronchial truncation sign, lobulation, burr sign, small bubbles, pleural indentation, vascular convergence sign, the lesions were more likely to be malignant tumors.