Head and Neck Imaging
The Value of Combination of ASL and DWI for Differentiating True Progression from Pseudoprogression of Malignant Glioma*
Author：BAI Yu-ping, ZHANG Jing, OU Yang-hong, et al.
affiliation：Department of MR, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China
PDFAbstract
Objective To explore the application of a combination of arterial spin labeling(ASL) and apparent diffusion coefficient (ADC) for differentiating true progression from pseudoprogression of malignant glioma. Methods The clinical and imaging data of 15 cases of true progression and 7 cases of pseudoprogression were retrospectively analyzed. The image of relative cerebral blood flow (CBF) and the values of apparent diffusion coefficient(ADC)were compared between abnormal enhancement area and contralateral normal area. Results High perfusion were shown in ASL in the patients with true progression, low perfusion in ASL in the patients with pseudoprogression. there were no statistical differences in ADC values between true progression and pseudoprogression. Conclusion ASL is valuable in differentiating true progression and pseudoprogression.
【Keyword】Malignant Glioma; True Progression; Pseudoprogression; Arterial Spin Labeling; Apparent Diffusion Coefficient
【Chart number】R739.41;R445.2
【Document Identification Number】A
【DOI】10.3969/j.issn.1672-5131.2018.08.001
Chinese journal of CT and MRI
th16Volume， th 8 Issue
2018Year08Month
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