Head and Neck Imaging
DCE-MR Appearances of Breast Cancer and Its Relationship with Microvessel Density*
Author:ZUI Hui-yan,CHEN Li-qun
affiliation:Department of Radiology, Guangdong Nongken Central Hospital, Zhanjiang 524002, Guangdong Province, China
PDFAbstract
Objective To observe the morphology and enhancement curve of MR dynamic enhanced scan in breast cancer, Analysis of the relationship between dynamic enhanced parameters and breast cancer microvessel density. Methods 30 cases of breast cancer patients with breast cancer between January 2012 and May 2015 were selected as the observation group, 30 cases of benign breast mass were the control group, Breast enhancement scan. MR dynamic enhanced and dynamic enhanced scanning time curves of breast cancer, The maximum linear slope (SS) of MR dynamic enhancement parameters in the two groups was measured and compared, Enhanced peak value (PH) Peak time (Tpeak) and signal intensity. The correlation of SS, PH, Tpeak and microvessel density (MVD) was observed. Results The dynamic enhancement of MR in breast cancer showed different degree enhancement,12 cases showed obvious enhancement,11 cases showed obvious enhancement, 5 cases showed peripheral enhancement, 3 cases showed mild enhancement. Dynamic enhanced scanning time curve showed that 22 cases were quickly rise and fall type, 8 cases showed a rapid rise platform type. The dynamic enhancement of MR in the observation group SS (2.4±0.7)%/s vs(1.2±0.3)%/s、PH(632.3±213.2)HU vs(456.3±135.4)HU Were significantly higher than the control group, Tpeak(52.3±13.2) t/s vs(78.6±28.3)t/s Significantly lower than the control group, The difference was statistically significant (P<0.01). The mean MVD of the observation group was42.3±12.8, Significantly higher than the control group of12.3±3.6, The difference was statistically significant (P<0.05). Correlation analysis showed that SS, PH and MR in breast cancer were positively correlated with MVD (r=0.723, 0.636),Tpeak was negatively correlated with MVD (r=-0.546), And had statistical significance (P<0.01). Conclusion The dynamic enhancement of MR in breast cancer lesions has a certain characteristic, Its quantitative measurement index can reflect the MVD.
【Keyword】Breast Cancer; Dynamic Enhanced MRI; Magnetic Resonance Imaging; Breast Cancer
【Chart number】R737.9
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2016.05.023
Chinese journal of CT and MRI
th14Volume, th 5 Issue
2016Year05Month
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