Objective To explore clinical value of digestive tract radiography and spiral CT for diagnosis of gastric cancer. Methods Thirty one gastric cancer patients admitted by the Radiology Department of the Hospital via pathologically definitive diagnosis were selected as research subjects, who were retrospectively analyzed and summarized according to clinical data, digestive tract radiography examination and spiral CT examination were respectively conducted , and examination findings of two diagnostic approaches were compared and analyzed based on results of pathological diagnosis. Results Digestive tract radiography results of 28 patients were diagnosed to be positive with coincidence rate at 90.3%. Spiral CT results of 29 patients were diagnosed to be positive, and the coincidence rate was 93.5%, and there was no statistical significance when two coincidence rates of diagnosis were compared. The sensitivity and specificity of digestive tract radiography hit 92.5% and 67.3% respectively, while such indexes of spiral CT hit 95.2% and 80.2% respectively, there was no outstanding significance in differences of such two indexed in two groups (P>0.05). Conclusion Digestive tract radiography and spiral CT delivers high value of application in the diagnosis of gastric cancer, the diagnosis accuracy is high, and there is no significant difference, being worthy of application and spread clinically.