Objective To investigate the VR+CTA imaging characteristics and clinical value of scoliosis. Methods A retrospective analysis of 38 scoliosis patients' VR+CTA imaging and clinic data from January 2013 to November 2015. Results The VR+CTA examination demonstrated that the descending aorta of scoliosis and rotation cases detour from the upper thoracic vertebrae(T5-7) to the right front of the vertebral body. The vertebral destruction (TB) cases with scoliosis possess signs of bone destruction, proliferation and vertebral deformation in the lower thoracic vertebrae, and the artery of upper thoracic vertebrae deformed into kyphosis concave and extended to the lower part. The vascular of spine deformation patients fills well and there is no calcified plaque as well. Meanwhile, the formation of vascular is normal, without any stenosis, expansion and filling defects. After VR+CTA examination of 38 patients, the situation of spine and its surrounding organs are clearly displayed, including the location of spinal deformation and vascular direction. Conclusion VR+CTA imaging can effectively diagnose the location and extent of scoliosis, degree and the relationship with the surrounding structure which helps patients to choose the appropriate clinical treatment and prognosis and is worthy of further promotion and application.