Objective To study the value of semi-quantitative parameters and quantitative parameters of dynamic contrast-enhanced magnetic resonance (MR) in the differential diagnosis of ovarian tumors. Methods The medical data of 67 patients with ovarian tumors who were admitted to our hospital were collected. All patients underwent dynamic contrast-enhanced MR scan in our hospital and they were given surgical treatment. According to the results of histopathology, the patients were divided into malignant ovarian tumor group (n=25) and benign ovarian tumor group (n=42). Semi-quantitative parameters and quantitative parameters of dynamic contrast-enhanced MR scan, including the time to peak (TTP), the maximum slope of increase (MSI), the maximum maximum slope of decrease (MSD), volume transfer constant (Ktrans) and rate constant (Kep) and extravascular extracellular space volume ratio (Ve) were calculated. The area under ROC curve, the maximum Youden index, the optimal threshold, the sensitivity, specificity, positive predictive value, negative predictive value and the total coincidence rate of semi-quantitative parameters and quantitative parameters in the differential diagnosis of benign and malignant ovarian tumors were analyzed according to ROC curve analysis. Results The TTP of malignant ovarian tumor group was significantly shorter than that of benign ovarian tumor group (P<0.05), the MSI, MSD, Ktrans, Kep and Ve were significantly higher than those in benign ovarian tumor group (P<0.05). According to ROC curve analysis, areas under ROC curve of semi-quantitative parameters TTP, MSI and MSD and quantitative parameters Ktrans, Kep and Ve were 0.859,0.820,0.747,0.903,0.887 and 0.736 respectively, the optimal thresholds were 85.044,72.963,30.582,0.156,0.390 and 0.108 respectively, the sensitivities were 84.3%,81.6%,75.2%,92.1%,97.4% and 80.3% respectively, and the specificities were 79.9%,67.2%,63.1%,77.9%,64.8% and 59.2% respectively. Conclusion Semi-quantitative parameters and quantitative parameters of dynamic contrast-enhanced MR scan are important supplement of conventional MR which can provide some help for doctors to identify benign and malignant ovarian tumors.