Head and Neck Imaging
The Diagnostic Value of MRI in the Localization of Intractable Temporal Lobe Epilepsy
Author：ZHAO Chun-lei,CHEN Zi-qian, QIAN Gen-nian,et al
affiliation：Department of Medical Imaging, Affilated Fuzhou Genneral Hospital of Nanjing Military Command, Fuzhou Clinical Medical College of the Second Military Medical University, Fuzhou 350025, China
PDFAbstract
Objective To evaluate the value of MRI in the localization of temporal lobe epileptic focus. Methods 21 healthy volunteers and 78 patients diagnosed as TLE were all examined by conventional MRI and 1 H-MRS. The accuracies of these two methods and combined application of the two methods were compared. Results We accurately diagnosed 26 and 46 patients using the routine MRI and 1 H-MRS examination respectively. After statistical analysis, we found the ratio of NAA/(Cho+Cr) was lower than that of the healthy side and corresponding value in healthy volunteers. As a result, we found the difference between conventional MRI and 1 H-MRS(χ2 =10.317,P=0.001), combined application(χ2 =12.443,P＜0.001) was statistically significant. We could not find the difference between the 1 H-MRS and the combined application were statistically significant(χ2 =0.107,P=0.744). Conclusion Conventional MRI and 1 H-MRS have great clinical application value in diagnosis of temporal lobe epilepsy, but the conventional MRI and 1 H-MRS examination should be carried out at the same time owing to the accuracy of 1 H-MRS was significantly higher than that of conventional MRI.
【Keyword】Magnetic Resonance Imaging; Spectroscopy; Temporal Lobe; Epilepsy; Localization
【Chart number】R816.1
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2016.03.010
Chinese journal of CT and MRI
th14Volume， th 3 Issue
2016Year03Month
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