Head and Neck Imaging
Application of Multimodal MRI in the Diagnosis and Treatment of Patients with Acute Ischemic Stroke
Author:YIN Liu-jie, ZHAO Song-yao, WANG Hong-ke, et al.
affiliation:Department of Neurology, Zhengzhou Central Hospital, Zhengzhou 450000, Henan Province, China
PDFAbstract
Objective To explore the effects of multimodal magnetic resonance imaging (MRI) in the diagnosis and treatment of acute ischemic stroke (AIS). Methods The clinical data of 210 patients with AIS who had a onset time from 4.5h to 9h in our hospital were analyzed retrospectively. Multimodal MRI diffusion-weighted imaging (DWI) and fluidattenuated inversion-recovery sequence (FLAIR) mismatching were used to screen patients with AIS in hyperacute phase, and the patients were divided into thrombolytic therapy group (observation group) and non-thrombolytic group (control group) according to whether they received thrombolytic therapy or not. The general data before treatment, clinical efficacy after treatment [National Institute of Health Stroke Scale (NIHSS), Daily Living Ability Rating Scale (BI)] and prognosis [BI after 90d of treatment, modified Rankin score (mRS)] were compared between the two group. Results Of the 210 AIS patients, 102 cases (48.57%) were with DWI/FLAIR mismatching and were judged to be AIS in hyperacute phase. Among them, 64 cases (62.75%, observation group) received thrombolytic therapy and 38 cases (37.25%, control group) were reluctant to receive thrombolytic therapy. There were no significant differences in the general data between the two groups (P>0.05). The NIHSS score after 7d of treatment and the mRS score after 30d of treatment in observation group were lower than those in control group (P<0.05), but the BI scores after 7d of treatment and after 90d of treatment were higher than those in control group (P<0.05). Conclusion Multimodal MRI can assist to evaluate patients with AIS in hyperacute phase, and screen the adaptation cases for thrombolytic therapy, and it can improve the clinical efficacy and promote the prognosis of AIS patients.
【Keyword】Acute Ischemic Stroke; Multimodal Magnetic Resonance Imaging; DWI; FLAIR; Thrombolysis
【Chart number】R743;R445
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2019.03.016
Chinese journal of CT and MRI
th17Volume, th 3 Issue
2019Year03Month
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