Objective To investigate the value of ultrasound and CT in the preoperative stages diagnosis of endometrial cancer. Methods The imaging data of 81 patients with endometrial cancer admitted to the hospital from January 2014 to February 2018 were retrospectively analyzed. All patients underwent transvaginal ultrasound and CT examination within two weeks before surgery, confirmed by pathology after surgery. The preoperative stages and lymph node metastasis were analyzed according to the results of imaging examination. Taking the postoperative pathological results as the golden standard, the diagnostic efficiencies for clinical stages and lymph node metastasis of endometrial cancer by the two methods were compared. Results The accuracy for the diagnosis of clinical stages of endometrial cancer by ultrasound was 75.31% (61/81). The above index by CT was 83.95% (68/81). The was no significant difference in the diagnosis accuracy by the two methods (P>0.05). The detection rate for the diagnosis of patients with endometrial cancer lymph node metastasis by CT was higher than that by transvaginal ultrasound (P<0.05). Conclusion Ultrasound and CT have similar diagnostic value for clinical stages of endometrial cancer. CT is superior in lymph node detection.