Objective To investigate the CT and MRI imaging features of hepatic sclerosing hemangioma. Methods The clinical data of 80 patients with hepatic sclerosing hemangioma admitted to our hospital were collected. All patients received the CT scan with 5mm slice thickness and reconstructed 5mm slice thickness, followed by the enhanced scan. After receiving intravenous injection of 60~75ml iopamidol, the enhancement pattern at hepatic arterial phase, portal venous phase and delayed phase were carried out. 4~5h later, patients received the MRI examinations. Thereafter, the appearance on the transversal T1WI and T2WI with and without fat suppression was obtained. Then the enhanced scan was performed after the injection of glucosamine glucosamine 0.1 mmol/kg with the same parameters as above, the thickness was 6mm and the matrix was 256×256. Results The plain scan showed that all lesions were of low density, and no enhanced image was found at the portal venous phase; While at the delayed phase, 98% of lesions were not enhanced, 2% lesions were unevenly enhanced. The MRI showed that there were 96 lesions, of which 85.42% lesions were located in the right lobe of the liver, 10.42% lesions were in the left lobe of the liver, 3.13% were in the caudate lobe and 3.13% were in the quadrate lobe. The single lesions were found in 78.13% and the 11.46% were multiple lesions. The tumor diameter of <2cm, 2~3cm, 4~5cm and >5cm accounted for 25.00%, 5.21%, 97.29% and 8.33%, respectively. The edge was unclear with low signal on T1WI and uneven mixed signal on T2WI. The detection rate of microcarcinoma was significantly higher in MRI than that of CT (P<0.05), and the misdiagnosis rate was lower than that of the CT (P<0.05). Conclusion The lesions of hepatic sclerosing hemangioma are mostly distributed in the right lobe of the liver. Compared with the MRI, the CT has high detection rate of the microcarcinoma.