Objective To explore MRI signs of astrocytoma, to improve preoperative diagnosis level and guide clinical treatment. Methods Clinical data, MRI features and pathological results of 27 patients with astrocytoma in our hospital from March 2014 to March 2016 confirmed by surgery and pathology were retrospectively collected, then analyzed and counted them. Results 27 cases were intracal solitary lesions, maximum diameter of lesions were 2.3cm-6.8cm, average diameter was (3.51±1.73)cm, diseased region were supratentorial in 16 cases, subtentorial 11 cases; MRI plain scan showed clear boundary in cystic and solid mass, solid part or solid mural nodule T1WI were low signal, T2WI were slightly higher signal; cystic part T1WI were obvious low signal, T2WI were obvious high signal, enhancement scanning showed solid part or solid nodule were obvious strengthening; partial solid mass had clear boundary, T1WI were slightly lower signal, T2WI were high signal, obvious strengthening occurred after enhancement scanning; diffusivity astrocytoma lesion had obscure boundary, abnormal signal or T1WI were low signal, T2WI were high signal, scan diffuse showed mild patchy strengthening or no obvious strengthening. Conclusion MRI imaging signs of astrocytoma are obvious, mainly in cystic and solid mass, partial solid mass, MRI signs can provide reference for the clinical diagnosis and treatment of astrocytoma.