Head and Neck Imaging

The Clinical Value of CT Spectral MultiParameter Imaging in Identification of HCC and FNH

Author:LU Fa-mei, LIU Hong-yan, LI Yu-xin

affiliation:Department of Radiology, MCH Hospital of Laiwu City, Laiwu 271199,Shandong Province, China

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Abstract

Objective Analyze the clinical value of CT Spectral multi-parameter imaging in identification of hepatocellular carcinoma(HCC) and focal nodular hyperplasia of the liver(FNH). Methods The CT spectral data of HCC and FNH of 44 cases from June 2012 to August 2014 in our hospital were collected and analyzed. Results The CT attenuation curve slope at arterial phase of HCC and FNH were (1.81±0.51 and (4.01±0.54), portal venous phase were (2.82±0.49) and (4.07±0.59), the energy spectrum CT attenuation curve slope between HCC and FNH is significant difference (P<0.05); In arterial phase, HCC and FNH has the best CNR at 50 keV, and portal venous phase, HCC has the best CNR at 70keV, FNH has the best CNR at 40keV; ROC curve maximum area corresponding to the arterial phase ICRLN, followed by portal venous phase NIC, the lowest for the portal venous phase ICRLN, the arterial phase ICRLN reference value was 4.175, sensitivity and specificity of differentiating hepatocellular carcinoma and FNH reached 100%. Conclusion The diagnostic value of CT multi-parameter imaging in differentiating HCC adn FNH is higher than normal CT, which can improve the accuracy of diagnosis.

【Keyword】Hepatocellular Carcinoma; Hepatic Focal Nodular Hyperplasia; Spectral Imaging

【Chart number】R445.3;R814.42

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2015.08.020