Head and Neck Imaging
Clinical Study of 1 H-MRS in the Diagnosis of Cerebral Neoplasms
Author：YAN Ying, LI Xian, CHEN Huai, et al.
affiliation：Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
PDFAbstract
Objective To explore the value of 1 H-MRS in the diagnosis and differential diagnosis of different intracranial neoplasms. Methods MRI and 1 H-MRS was performed in 61 patients confirmed to be high grade glioma, meningioma and solitary metastases. For each case, the NAA, Cr and Cho was measured in enhanced region, peritumoral region and contralateral normal-appearing white matter (CNAWM), the Cho/NAA, Cho/Cr, NAA/Cr was calculated and compared among three ROIs respectively. Results Compare to the normal region, the Cho/Cr, Cho/NAA in enhanced region of three lesions and peritumoral of glioma were higher (P<0.01), NAA/Cr were lower (P<0.01). In enhanced region, NAA/Cr in meningioma was lower than glioma and metastases (P<0.01) and Cho/NAA was higher than them (P<0.01). In peritumoral region, Cho/Cr, Cho/NAA in glioma were higher than meningioma and metastases(P<0.01) and NAA/Cr was lower than them(P<0.01). Conclusion As a supplement of routine MRI, 1 H-MRS plays an important role in the differential diagnosis of different intracranial neoplasms.
【Keyword】1 H-MRS; Glioma; Metastases; Meningioma
【Chart number】R651.1
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2017.06.002
Chinese journal of CT and MRI
th15Volume， th 6 Issue
2017Year06Month
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