Head and Neck Imaging

Diagnostic Value of Tumor Markers Combined with Multi-slice Spiral CT in Patients with Early Lung Cancer*

Author:ZHU Xiao-feng, ZOU Zhi-tian, XU Chuan-bing

affiliation: Jiamusi University First Affiliated Hospital Thoracic Surgery, Jiamusi 154002, Heilongjiang Province, China

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Abstract

Objective To investigate the clinical value of tumor marker combined with multi-slice spiral CT in the diagnosis of early lung cancer. Methods Sixty-two patients with lung cancer admitted to our hospital between March 2012 and March 2016 were selected as the study subjects. The tumor marker detection and spiral CT examination were performed. The spiral CT features of SQC, ADC, SCLC and other types of lung cancer were summarized. The sensitivities of tumor markers and the combined diagnosis of lung cancer were calculated respectively. Results The coincidence rate of Cyfra21-1 in the diagnosis of SQC was the highest, which was 71.4% (20/28). The coincidence rate of CEA in the diagnosis of ADC was the highest, which was 70.8% (17/24); The coincidence rate of NSE in the diagnosis of SCLC was the highest, which was 70% (7/10). The coincidence rate of combined diagnosis of tumor markers was 80.6% (50/62) while the coincidence rate of tumor markers combined with spiral CT in the diagnosis of lung cancer was 93.5% (58/62) (χ2 =4.593, P=0.032). Conclusion The coincidence rate of tumor markers combined with multi-slice spiral CT in the diagnosis of early lung cancer is high, with high clinical application value.

【Keyword】Lung Cancer; Tumor Marker; Spiral CT

【Chart number】R734.2

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2017.06.014