Objective To explore the evaluation value of enhanced MRI scan in the prognosis of patients having intracranial glioma surgery. Methods 30 cases of patients with intracranial gliomas treated in our hospital from January 2014 to April 2015 were taken as the research objects. All of the patients were confirmed by surgery and pathology. Enhanced MRI scan was performed regularly before and after operation. The MRI findings were observed. Results In postoperative 3d, MRI reexamination indicated reactional enhancement in 4 cases, most of which manifested as homogeneous and ring or sheet enhancement, tumor residual in 6 cases with irregular shape, nodules or mass enhancement on tumor edge. Tumor recurrence occurred in 9 cases (a cases of recurrence in postoperative 3 months, 8 cases in 6 to 18 months). MRI showed new lesions in the operation area or around the operation area. Enhanced scan indicated irregular garlandlike or nodule enhancement. In postoperative 1 to 3 months, postoperative misdiagnosed 6 cases (5 cases of reactional enhancement misdiagnosed as tumor residual and a case of tumor recurrence). Conclusion Enhanced MRI scan performed in postoperative 3d is of very important significance in accurately displaying the resection degree (tumor residual) after tumor surgery, formulating following therapy plan and evaluating the prognosis of the patients.