Head and Neck Imaging

Clinical Study of Low-dose 70kv.50mAs MSCT Perfusion Imaging in the Evaluation of Patients with Lung Cancer

Author:FENG Jun, GAO Dei-pei, LI Zhen-hui, et al.

affiliation:Department of Radi ology, The 3rd Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming 650118, Yunnan Province, China

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Abstract

Objective To investigate the clinical value and feasibility of low-dose 70kv.50mAs MSCT perfusion imaging in the evaluation of patients with lung cancer. Methods Retrospectively studied 45 cases(squamous carcinoma 15 cases, adenocarcinoma 23cases, small cell carcinoma 7cases) lung cancer confirmed by operation and pathology, these patients were undergone low-dose(70kv.50mAs)MDCT perfusion scanning before operation. The original images were processed by perfusion software. The value of time to peak(TTP), blood flow (BF), blood volume (BV) and permeability (PMB) were calculated, and gained perfusion image. Results The TTP (s) of squamous carcinoma, adenocarcinoma, small cell carcinoma were 15.62、17.91、16.89. The BF (ml/100ml/ min) of squamous carcinoma, adenocarcinoma, small cell carcinoma were 91.72, 77.27, 90.60;The BV (ml/100ml) of squamous carcinoma, adenocarcinoma, small cell carcinoma were 8.06, 8.94, 11.94. The PMB(ml/100ml/min)of squamous carcinoma, adenocarcinoma, small cell carcinoma were 13.79, 15.17, 13.95. Conclusion The lowdose(70kv.50mAs)MSCT perfusion scanning could gained good perfusion image and calculated tumor's value of TTP, BF, BV, PMB, it was a effective evaluation analysis for tumor's blood supply and perfusion.

【Keyword】Lung Cancer; Tomography; X-ray Computed; Perfusion; Low-dose

【Chart number】R734.2;R445.3

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2016.02.015