Objective Research and analysis the 64-slice spiral CT scan clinical value of symptomatic carotid stenosis. Methods The institutes will be admitted 76 cases of patients with cerebrovascular disease types grouped according to the control group and the observation group, 38 cases each. Patients with non-ischemic control group were cerebrovascular disease; observation group for patients were ischemic cerebrovascular disease; group 2 patients were treated with 64-slice spiral CT, and for two groups of patients with bilateral carotid artery plaque type, degree of stenosis evaluation and Analysis. Results The study found that patients with carotid artery stenosis observation group was 78.95% (30/38) significantly higher than 36.84% (14/38) (P<0.05); observation group segments vessels mainly in the soft spot based, However, in the control group mainly hard plaque based. Conclusion Patients with clinical use of 64-slice spiral CT vascular occlusion and stenosis can be effectively used in clinical diagnosis to determine the number and nature of plaque inside the arteries of patients, but also effectively assessed. Therefore, clinical application of 64-slice spiral CT in diagnosis of symptomatic carotid stenosis is extremely important diagnostic value, thus providing an important reference for clinical treatment options.