Head and Neck Imaging

Computer-aided Differential Diagnosis of Adenocarcinoma Insitu and Atypical Adenomatous Hyperplasis Which Appear as Ground Glass Opacity*

Author:JIAO Na, WU Ming-xiang, GONG Jing-shan,et al.

affiliation:Department of Radiology, Shenzhen People's Hospital,Shenzhen 518000, P.R.China

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Abstract

Objective To study the clinical application value of computer-aided diagonosis in differentiating atypical adenomatous hyperplasia from adenocarcinoma insitu. Methods 125 cases of ground glass opacity detected by CT were diagonosized by self-designed soft, to compare the difference between AIS and AAH. Results There was no significant difference in lesion size between AIS and AAH (P>0.05). The peak and mean CT value of AAH were obviously lower than that of AIS,with significant difference (P<0.001). If the peak of CT value<-620,it was more likely to be AAH. In the CT histogram, doublepeak or multi-peak can except for the possibility of AAH. Conclusion Tissue components analysis basede on computer-aided diagonosis can perfectly identify AAH and AIS which appear as ground glass nodules.

【Keyword】Computer-aided Diagonosis; Ground Glass Nodules; Lung Neopalsms

【Chart number】R322.3+5

【Document Identification Number】A

【DOI】10.3969/j.issn.1672-5131.2015.06.010