Objective To explore the clinical significance and imaging features of collateral vessels in the portal hypertension of hepatic cirrhosis. Methods 92 hospitalized cases of hepatic cirrhosis from February, 2013 to September, 2015 were collected, including the clinical data of hepatic encephalopathy, ascites and albumin, prothrombin time, etc. All the cases were classified into three groups according to Child-Pugh classification standard and they were all examined CT portal venography. All the images were given image postprocessing such like VR (Volume Rendering), MIP(Maximun Intensity Projection), et al. The data of different collateral vessels were used to analyzed the relationship of themselves and their connection with the clinical manifestations and laboratory tests. Results CT portal venography can show the beginning and end, route and forms of different collateral varices clearly. The occurance rate of esophageal vein, Paraesophageal vessels, paraumbilical vein increased by the worse liver function(P＜0.05). The width enlargement of left gastric vein lead to more collateral varices(P＜0.05)； Paraesophageal vessels can reduce the occurance of esophageal varices(P＜0.05) rather than gastric varices(P＞0.05); The occurance rate of ascites increased while there were esophageal, Paraesophageal, gastric or paraumbilical varices(P＜0.05). The difference between the laboratory tests such as albumin, prothrombin time, total bilirubin and the amount of collateral vessels was not statistically significant(P＞0.05). Conclusion CT portal venography is a dominant technique to show the beginning and end, route and forms of different collateral circulation which can provide objective base to clinical diagnosis and treatment. It is important to understand the relationship between each other and their relationship with clinical manifestation for the disease assessment and prognostic judgement.