Head and Neck Imaging

Application of Semi-Quantitative Parameters of Dynamic Contrast-Enhanced MRI in Prostate Cancer*

Author:CHEN Jie, REN Yong-fang, QU Yuan

affiliation:Department of Radiology and Medical Imaging, People's Hospital of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang, 830001,P.R.China

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Abstract

Objective By analyzing the LAVA dynamic enhanced magnetic resonance (DCE-MRI) related parameters to evaluate the diagnostic value of DCE-MRI for prostate cancer. Methods 29 patients with PCa and 58 BPH patients with liver histopathology confirmed the line fast volume acquisition sequence (LAVA) multiphase dynamic enhanced scan, access SI-T curve, and calculate the peak time (Tmax), the maximum signal strength (Slmax %), enhancement ratio (R), out of scores (washout), compare the differences in the parameters between PCa, gBPH, sBPH of, and ROC curve analysis. Results PCa group SI-T curve at a speed drop liter main type, gBPH, sBPH platform-type-based group; between Tmax, R, Washout three groups was statistically significant (P<0.05) differences between the groups was not Slmax% statistically significant (P>0.05); Tmax, R, Washout value between gBPH and sBPH group showed no significant difference (P>0.05); area under the ROC curve Tmax largest diagnostic sensitivity and specificity were 93.6%, 84.6%; PCa group within Tmax more (75.9%) one minute, sBPH group more in Tmax (55.5%) for 1-2 minutes, and two more in gBPH group Tmax range, ie 1-2 minutes (42.5%) and after 2 minutes (40.0%). Conclusion Semi-quantitative analysis of DCE-MRI has a higher value in the diagnosis of prostate cancer can be used for differential diagnosis of benign and malignant prostate lesions

【Keyword】Prostate Cancer; Liver Volume Accelerated Imaging; Dynamic Contrastenhanced

【Chart number】R445.2;R737.25

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2016.01.031