Objective To investigate the clinic value of using stress myocardial perfusion imaging combined with dual source CT coronary artery imaging to predict effect of percutaneous coronary intervention(stent implantation). Methods 28 patients of CAD with stent implantation underwent MPI before(1 week)and after PCI procedure respectively and the results of MPI and DSCT were compared. Results Before stent implantation of SDCT and CAG showed the stenosis lesions in left coronary artery accounted for the majority, 33, of which the anterior descending branch more, 24; right coronary artery in 13, consistent with the results of coronary artery angiography. Before and after the implantation of stents, coronary stenosis is improved obviously. The amount of segments of ischemic myocardium after PCI was less than those before PCI significantly and the segments of infarct myocardium were similar. The values of SSS and SDS after PCI were lower than those before PCI significantly. After stent implantation the value of LVEF was higher, while the values of IVEDV and LVESV were lower rather than those before PCI. Conclusion MPI combined with SDCT has important clinical value to predict the effect of PCI．