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·腹部疾病·

妊娠合并麻疹46例临床分析*

作者:龙 滨 李 晶 郭晓峰 樊银欢

所属单位:广东省广州市第八人民医院妇产科 (广东 广州 510060)

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摘要

目的 探讨妊娠合并麻疹的流行病学特点、临床特征、对母儿的不良影响及妊娠转归。方法 回顾性分析我院2012年 1月-2014年12月收治的46例妊娠合并麻疹患者的流行病学史、临床资料,重点分析妊娠合并麻疹对母儿的影响和妊 娠转归。结果 22例早、中期妊娠者发生流产及死胎9例,占19.5%,24例晚期妊娠患者中1 例早产;8 例剖宫术;2 例新生儿出现麻疹。结论 孕早期感染麻疹,病毒影响神经系统可以使早期及晚期流产率上升,孕中、晚期感染麻 疹易导致死胎和早产,中、晚期应积极治疗,减少并发症、死胎和早产的发生。

Objective Further understanding the epidemiologic features of pregnancy combined measles, the clinical manifestation, the maternal-fetal adverse effects, and the prognosis. Methods A retrospective study was performed on 46 cases of pregnancy combined measles during January 2012 to December 2014, the analysis was emphasized on both maternalfetal effects and its prognosis. Results 22 of 46 cases were in first and second trimester, the other 24 cases were third trimester pregnancy. 9 of the 22 (19.5%) ended in miscarriage or still birth. 1 premature delivery, 8 c-section and 2 neonatal measles were observed among the 24 late pregnancy patients. Conclusion Viral effects on nervous system may increase the possibility of miscarriage in first and second trimester when maternal infection happens in early pregnancy. Contracting in second and third trimester may lead to still birth and premature delivery. Active intervention is suggested to be given from second trimester to diminish the complication, still birth and premature birth.

【关键词】麻疹;妊娠;妊娠转归

【中图分类号】R511.1

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2016.02.016

前言

麻疹是由麻疹病毒引起的急性传染病,传染性极 强,多见于儿童。其临床特征为发热、流鼻涕、咳 嗽、眼结合膜炎,出现特殊的科氏斑(又称麻疹黏膜 斑)和广泛的皮肤斑丘疹。麻疹一般康复顺利,但也 可引起严重并发症甚至危及生命。妊娠妇女感染麻疹 病毒后病情相对较重,易并发肺炎,也可导致不良妊 娠结局。本文回顾性分析我院2012年1月~2014年12 月收治的妊娠合并麻疹46例,报道如下。