论著-头颈部
常规MRI联合DWI在 宫颈癌术前分期诊 断中的应用价值
作者:李风莲1 周 玲2
所属单位:1.河南省鹤壁市人民医院核磁共振 室 (河南 鹤壁 458030) 2.湖北省襄阳市中心医院(湖北文 理学院附属医院)放射科 (湖北 襄阳 441021)
PDF摘要
目的 探究常规磁共振成像(MRI) 联合扩散加权成像(DWI)在宫颈癌术前分 期诊断中的应用价值。方法 纳入2016年 9月-2018年9月我院56例宫颈癌患者展开 回顾性分析,术前行常规MRI联合DWI检 查,测量肿瘤组织及残存正常宫颈组织 的表观扩散系数(ADC)值,并以术后病理 分期为金标准,比较常规MRI扫描与常规 MRI联合DWI扫描对宫颈癌术前分期诊断准 确性的差异。结果 宫颈癌实性部分ADC 值(0.88±0.32)×10-3mm2 /s显著高于残 存正常宫颈组织ADC值(1.58±0.20)×10- 3 mm2 /s,差异有统计学意义(t=13.882, P<0.001);MRI联合DWI对宫颈癌术前分 期诊断准确性显著高于常规MRI,差异有 统计学意义(χ2 =5.617,P=0.040)。结论 宫颈癌患者术前行常规MRI联合DWI检查是 一种可信、准确度高的影像学诊断方法, 可准确评估术前分期,指导治疗方案的选 择及预后评估。
Objective To investigate the value of conventional magnetic resonance imaging (MRI) combined with diffusion-weighted imaging (DWI) in preoperative staging of cervical cancer. Methods A total of 56 patients with cervical cancer who admitted to the hospital from September 2016 to September 2018 were selected for retrospective analysis. Conventional MRI combined with DWI was performed to measure the apparent diffusion coefficient (ADC) value of tumor tissues and residual normal cervical tissues. With postoperative pathological staging as the golden standard, the accuracy of preoperative staging of cervical cancer was compared between conventional MRI scan and conventional MRI combined with DWI scan. Results The ADC value of the solid part of cervical cancer was significantly higher than that of the residual normal cervical tissue [(0.88±0.32)×10-3mm2 /s vs (1.58±0.20)×10-3mm2 /s] (t=13.882, P<0.001). The accuracy of MRI combined with DWI for preoperative staging of cervical cancer was significantly higher than that of conventional MRI (χ2 =5.617, P=0.040). Conclusion Preoperative conventional MRI combined with DWI is a reliable and accurate imaging diagnostic method for cervical cancer. It can be used to assess the preoperative stage accurately, and guide the choice of treatment plan and evaluate the prognosis.
【关键词】磁共振成像;扩散加权成像; 宫颈癌;术前分期
【中图分类号】R737.33;R445.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.06.031
前言
宫颈癌为女性生殖系统常见恶性肿瘤,发病率仅次于乳腺癌,随 着近年来人们生活习惯改变及精神压力增加,其发病群体逐渐偏年轻 化[1-2]。宫颈癌早期无明显症状,随病情进展常伴阴道流血、排液、尿 频、尿急等症状,或出现肾盂积水、尿毒症等并发症,死亡率居女性 生殖系统恶性肿瘤首位[3]。早期诊断、术前准确分期有助于指导临床 治疗方案的制定,提高患者生存率。磁共振成像(MRI)属无创检查,可 反复操作,多方位、多参数成像,软组织分辨率高,临床应用价值较 高[4]。扩散加权成像(DWI)显示病变与水分子扩散运动有关的病变,并 提供表观扩散系数(ADC)值量化指标,在宫颈癌诊断中的应用受到广泛 关注[5]。本研究探讨常规MRI联合DWI在宫颈癌术前分期诊断中的应用价 值,为宫颈癌的临床诊断及治疗选择提供依据。现报道如下。
中国CT和MRI杂志
第17卷, 第 6 期
2019年06月
相关文章