论著-头颈部
CT血管造影点征对 早期脑出血患者预 后的评估价值分析
作者:孙凌云1 王海全1 邓绍强2 王 湘1 张晓强1 何新民2
所属单位:1.四川大学华西广安医院神经外科 2.四川大学华西广安医院放射科 (四川 广安 638000)
PDF摘要
目的 探讨CT血管造影(CTA)点 征对早期脑出血患者预后的评估价值。 方法 回顾性分析2016年7月-2018年7月 我院收治的48例早期脑出血患者的临床 资料。发病6h内行急诊头颅CT平扫和CTA 检查,根据CTA原始图像是否存在点征将 48例患者分为2组。若患者病情恶化则及 时复查CT,或发病24h后复查,计算血肿 量,比较2组患者初诊和复诊血肿体积变 化情况,评估CTA点征对血肿扩大的预测 价值。结果 48例患者中点征阳性12例 (25.00%),点征阴性36例(75.00%);点征 阳性者复诊血肿体积显著高于初诊血肿体 积,且明显高于点征阴性者(P﹤0.05),点 征阴性者初诊和复诊血肿体积比较,差异 无统计学意义(P﹥0.05);CTA点征单独预 测血肿扩大的灵敏度为73.33%(11/15), 特异度为96.97%(32/33),准确率 为89.58%(43/48),阳性预测值为 91.67%(11/12),阴性预测值为 88.89%(32/36)。结论 CTA点征可为早期 脑出血患者预后提供客观影像学指标,预 测血肿扩大的准确性较高,有助于筛选出 可能发生血肿扩大的高危患者,使这类患 者治疗更为及时和准确。
Objective To explore the evaluated value of CT angiography (CTA) dot signs on the prognosis in patients with early cerebral hemorrhage. Methods The clinical data of 48 patients with early cerebral hemorrhage admitted to our hospital from July 2016 to July 2018 were retrospectively analyzed. The patients were given emergency CT plain scan and CTA examination within 6 h after onset, and 48 patients were divided into two groups according to whether there were any dot signs in the original CTA images. If the patient' s condition deteriorated, CT would be reviewed in time or review was given at 24 h after onset. The amount of hematoma was calculated, and the changes of hematoma volume at initial visit and return visit were compared between the two groups, and the predictive value of CTA dot signs on hematoma enlargement was evaluated. Results Among the 48 patients, 12 cases (25.00%) were with positive dot signs and 36 cases (75.00%) were with negative dot signs. The hematoma volume at return visit in patients with positive dot signs was significantly higher than that at initial visit, and was significantly higher than that in patients with negative dot signs (P<0.05), and there was no significant difference in the hematoma volume between initial visit and return visit in patients with negative dot signs (P>0.05). The sensitivity, specificity, accuracy rate, positive predictive value and negative predictive value of CTA dot signs in predicting hematoma enlargement were 73.33% (11/15), 96.97% (32/33), 89.58% (43/48), 91.67% (11/12) and 88.89% (32/36). Conclusion CTA dot signs can provide objective imaging indicators for the prognosis of patients with early cerebral hemorrhage. And it has high accuracy in the prediction of hematoma enlargement, and it is helpful for screening high-risk patients who may be with hematoma enlargement, so that these patients can be treated more timely and accurately.
【关键词】CT血管造影;点征;脑出血; 血肿扩大
【中图分类号】R743.34
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2019.06.003
前言
脑出血是脑卒中中最危险、最具破坏性的一种类型,不仅在脑血 管疾病中发病率较高,还具有致残率高、致死率高、预测性差的特 点。血肿体积大小是影响患者存活率和神经功能预后的最重要指标, 血肿扩大会导致预后不良,因此临床上需寻找可靠易检查的指标预测 血肿扩大和评估脑出血预后水平,为临床治疗方案的选择提供依据[1]。 随医学影像学的发展和进步,CT血管造影(CTA)在评估脑出血预后方面 有较为广泛的应用,其原始图像点征与血肿局部活动性出血有关,在 预测血肿扩大和临床疗效中发挥重要作用[2]。有研究表明,患者发病 6h以内接受CTA检查的点征检出率较高,是预测血肿扩大的重要独立因 素[3]。本研究旨在探讨CTA点征对早期脑出血患者血肿扩大的预测价值 和预后的评估价值,现报道如下。
中国CT和MRI杂志
第17卷, 第 6 期
2019年06月
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