论著-头颈部
超声、MSCT及MRI对 肝门部胆管癌的诊 断价值比较
作者:单连强1 石士奎2 王大巍3
所属单位:1.蚌埠医学院第二附属医院放射科 (安徽 蚌埠 233040) 2.蚌埠医学院第一附属医院放射科 (安徽 蚌埠 233004) 3.蚌埠医学院第二附属医院脑外科 (安徽 蚌埠 233040)
PDF摘要
目 的 比 较 超 声 、 多 层 螺 旋 CT(MSCT)及磁共振成像(MRI)对肝门部胆 管癌(HC)的诊断价值。方法 研究对象为 本院自2014年1月-2018年8月收治的35例 拟诊HC患者,回顾性分析其超声、MSCT、 MRI影像资料及手术病理结果,以病理为 状态变量,超声、CT、MRI等为检验变量 绘制受试者工作特征曲线(ROC)分析其诊 断价值。结果 经ROC曲线分析,超声、 MSCT、MRI曲线下面积值分别为0.690、 0.782、0.838,以MRI曲线下面积值(AUC) 最高,提示其诊断效能最佳,对应敏感 度及特异度分别为92.60%、75.00%;两 两联合诊断中,MSCT联合MRI诊断AUC最 高,为0.940,对应敏感度及特异度分 别为77.80%、100.00%;超声、MSCT、 MRI联合诊断时曲线下面积值略有上升 (AUC=0.940),但对应敏感度及特异度与 MSCT联合MRI诊断一致。结论 较单一超声 或MSCT,MRI诊断HC时敏感度最佳,联合 MSCT可获取更佳诊断效能,值得临床推 介。
Objective To compare the diagnostic values of ultrasound, multi-slice spiral CT (MSCT) and magnetic resonance imaging (MRI) in hilar cholangiocarcinoma (HC). Methods The study objects were 35 HC patients undergoing selective diagnosis who were admitted to the hospital from January 2014 to August 2018.The retrospective analysis was performed onimaging data of ultrasound, MSCT and MRI, and results of surgical pathology. Taking pathology as state variable, ultrasound and CT and MRI as test variable, the receiver operating characteristic (ROC) curve was drawn to analyze their diagnostic values. Results ROC curve showed that the areas under the curve of ultrasound, MSCT and MRI were 0.690, 0.782 and 0.838, respectively. The area under the curve (AUC) of MRI was the highest, suggesting that its diagnostic efficiency was the best. The corresponding sensitivity and specificity were 92.60% and 75.00%, respectively. In the combination diagnosis of any two of them, AUC of MSCT combined with MRI was the highest (0.940), the corresponding sensitivity and specificity were 77.80%, 100.00% respectivel. the AUC of ultrasound combined with MSCT and MRI was slightly increased (AUC=0.940). But the corresponding sensitivity and specificity were consistent with those of MSCT combined with MRI. Conclusion Compared with that of single ultrasound or MSCT, the sensitivity of MRI is the best for the diagnosis of HC. The diagnostic efficiency of MRI combined with MSCT is better. It is worthy of clinical recommendation.
【关键词】超声;多层螺旋 CT;磁共振 成像;肝门部胆管癌
【中图分类号】R575.7
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.06.026
前言
肝门部胆管癌(hilar cholangiocarcinoma,HC)占胆道肿瘤的 50%~70%,系指累及肝总管、左右肝管及其汇合部的胆管黏膜上皮肿 瘤,生物学特征显示其肿瘤体积小、恶性程度高,且极易侵犯肝实 质,根治性切除仍是HC的最佳根治方式[1-2]。早期患者仅表现为消瘦、 右上腹部疼痛等非特异性临床症状,随着疾病进展,待出现黄疸、全 身瘙痒等症状就诊时,多数已失去手术根治机会[3-4]。因此,HC的早期 诊断尤为重要。超声、多层螺旋CT(muiti-slice spiral,MSCT)及磁共 振成像(magnetic resonanceimaging,MRI)是临床常见的影像学辅助检 查方式,其在疾病的诊断鉴别、手术方案制定及预后评估上发挥重要 价值;三种影像学方式在HC中的临床应用虽并不鲜见,但不同报道结 论仍存在一定歧义[5-7]。鉴于此,本研究拟通过回顾性分析方式对本院 收治的拟诊HC患者的超声、MSCT、MRI影像资料,拟对照研究方式比较 三种影像学辅助检查手段对HC的诊断价值,进一步补充及完善HC的临 床诊断。具体报道如下。
中国CT和MRI杂志
第17卷, 第 6 期
2019年06月
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