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CTA在主动脉夹层诊 断及介入治疗效果 评估中的应用

作者:张宪亮

所属单位:河南省周口市中心医院介入科 (河南 周口 466000)

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摘要

目的 探讨CT血管造影(CTA)在主 动脉夹层(AD)诊断及介入治疗效果评估中 的应用价值。方法 回顾性分析2015年1 月-2017年12月我院收治的36例AD患者临 床资料,病例患者均行DSA和CTA检查,评 估CTA诊断AD患者原发破口位置的准确性 以及Debakey分型准确性,同时分析CTA在 AD介入治疗效果评估中价值。结果 以DSA 诊断结果为金标准,CTA诊断AD患者原发 破口位置的准确率为86.11%,CTA诊断AD 患者Debakey分型的总体准确率97.22%; 25例Debakey Ⅲ型AD患者接受覆膜支架腔 内修复术治疗,术后两周复查CTA发现7例 急性患者出现Ⅰ型近端内漏,为患者行内 科保守治疗后自愈,余12例急性AD和6例 慢性AD患者术后两周复查CTA均发现假腔 内有血栓形成但未见并发症存在,手术成 功率100%,近期死亡率为0,术后6个月随 访发现1例死亡,死亡率4.00%。结论 CTA 对AD诊断有非常重要价值,在临床实践工 作中可为AD患者介入治疗后近期疗效评估 提供重要参考信息。

Objective To investigate the application value of CT angiography (CTA) in the diagnosis of aortic dissection (AD) and the evaluation for the curative effect on interventional therapy. Methods The clinical data of 36 patients with AD admitted to the hospital from January 2015 to December 2017 were analyzed retrospectively. All patients underwent DSA and CTA examination. The accuracies of CTA for the diagnosis of the primary break location of AD patients and Debakey types were evaluated. The value of CTA in the evaluation for the curative effect on AD interventional therapy was analyzed. Results Taking the DSA diagnosis results as the golden standard, the accuracy of CTA in the diagnosis of primary break location of AD patients was 86.11%. The overall accuracy of CTA in the diagnosis of Debakey types of AD patients was 97.22%. A total of 25 AD patients of Debakey III type were given transluminal stent-graft placement. After 2 weeks of the surgery, CTA reexamination found there were 7 acute cases with type I proximal endoleak. The patients were self-healing after given medical conservative treatment. Among the remaining 12 cases with acute AD and 6 cases with chronic AD, CTA reexamination after 2 weeks of the surgery found that there was thrombosis in the pseudocoele but no complications. The success rate of surgery and the recent mortality were 100% and 0, respectively. There was 1 case died after 6 months of surgery by followup. And the mortality was 4.00%. Conclusion CTA is of great value in the diagnosis of AD. It can provide important reference information for the short-term curative effect evaluation of AD patients after interventional therapy in clinical practice.

【关键词】主动脉夹层;双源CT血管造 影;介入治疗;效果评估

【中图分类号】R543.16;R814.42

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.06.023

前言

主动脉夹层(Aortic dissection,AD)系指主动脉腔内的血液沿主 动脉内膜破裂处进入主动脉中膜,导致中膜分离,且从主动脉长轴方 向扩展最终形成主动脉壁的真假两腔分离状态[1],流行病学指出AD较少 见,每年发病率约为10万分之一至二十万分之一,以疼痛、高血压、下 肢缺血及肾脏缺血等临床症状较为常见[2]。现代医学指出当血管壁正常 结构被破坏时夹层区域血管易破裂,导致大量血液涌入胸腔及腹腔,危 及患者生命安全[3]。AD准确诊断是确保患者良好预后的关键,而目前AD 快速准确诊断是困扰临床医师的重要问题,近期研究证实CT血管造影 (CT angiography,CTA)对AD患者有一定诊断价值[4],而本文旨在探究 CTA在主动脉夹层诊断及介入治疗效果评估中的应用价值,具体结果如 下。