论著-头颈部
心肌炎儿童MRI表现 及其与心功能生化 指标的关系分析
作者:吴清岩1 孙建军2 马丽娜1
所属单位:1.濮阳油田总医院儿科 (河南 濮阳 457001) 2.濮阳油田总医院放射科 (河南 濮阳 457001)
PDF摘要
目的 分析心肌炎儿童核磁共振 (MRI)表现及其与心功能生化指标的关 系。方法 回顾性分析2016年5月-2018年 5月我院收治的32例心肌炎患儿的临床资 料,选择同时期体检健康的儿童共18例作 为对照。所有儿童均接受心脏MRI检查, 检测血清心肌肌钙蛋白T(cTnT)、N端脑 钠肽前体(pro-BNP)水平。以临床诊断结 果作为对照,评价心脏MRI对儿童心肌炎 的诊断价值,比较MRI对不同浓度cTnT、 pro-BNP心肌炎儿童的检出率。结果 心脏 MRI检查诊断心肌炎的灵敏度、特异度、 准确率为62.50%、94.44%、74.00%,约 登指数为0.57,kappa值为0.502,与临 床诊断结果的吻合度一般;心脏MRI检查 对cTnT﹥140ng/L、pro-BNP﹥614ng/L的 儿童检出率均高于cTnT≦140ng/L、proBNP≦614ng/L的儿童(P﹤0.05)。结论 心 肌炎儿童的MRI图像表现具有特异性,且 对cTnT、pro-BNP浓度异常升高的患儿有 更高的检出率。
Objective To analyze the magnetic resonance imaging (MRI) findings and their relationship with biochemical markers of cardiac function in children with myocarditis. Methods The clinical data of 32 children with myocarditis admitted to our hospital from May 2016 to May 2018 were analyzed retrospectively. A total of 18 children with healthy physical examination were selected as control group. All children were given cardiac MRI, and the levels of serum cardiac troponin T (cTnT) and N-terminal pro-brain natriuretic peptide (pro-BNP) were detected. The clinical diagnostic results were used as controls to evaluate the diagnostic value of cardiac MRI on children with myocarditis. The detection rates of MRI in myocarditis children with different concentrations of cTnT and proBNP were compared. Results The sensitivity, specificity and accuracy of cardiac MRI in the diagnosis of myocarditis were 62.50%, 94.44% and 74.00%, and the Yodenindex was 0.57 and the kappa value was 0.502 with a general consistency with the clinical diagnosis results. The detection rates of cardiac MRI in children with cTnT>140ng/L and proBNP>614ng/L were higher than those in children with cTnT≦140ng/L and proBNP≦614ng/L (P<0.05). Conclusion MRI images of children with myocarditis are specific and children with elevated A and B indicators had higher detection rates..
【关键词】心肌炎;MRI;cTnT;pro-BNP
【中图分类号】R542.2+1
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.06.019
前言
心肌炎是一种由感染或非感染因素引发的心肌细胞变性、坏死及 纤维组织增生等病理变化的心肌炎性疾病,可累及心内膜、心包,多 发于儿童时期,不利于患儿健康。心肌炎的临床表现不具有特异性, 且儿童难以准确描述自身症状及感受,因此心肌炎诊断一直是临床上 的难题。心内膜心肌活检(EMB)是心肌炎诊断的“金标准”,但该检查 有创、对机体损伤较大,尤其难以被儿童家属接受。目前临床上对心 肌炎的诊断主要依赖于临床症状和心电图、超声心电图、实验室检查 等多方面综合判断。核磁共振(MRI)具有高分辨率、无创、可多次检查 等优势,在儿童心脏疾病诊断中有较频繁的应用。本研究旨在探讨儿 童心肌炎的MRI表现及诊断价值,分析其与心肌损伤指标的关系,现报 道如下。
中国CT和MRI杂志
第17卷, 第 6 期
2019年06月
相关文章