摘要
目的 探讨彩色多普勒超声血流 显像(CDFI)与弥散加权成像(DWI)应用于 甲状腺癌术前诊断的临床价值。方法 回 顾性分析30例甲状腺癌患者临床资料, 以术中淋巴结清扫病理标本组织学检查 结果为“金标准”,分析术前CDFI、DWI 及二者联用对其颈部淋巴结转移情况的诊 断效能差异。结果 DWI及二者联用诊断 中央区、颈侧区淋巴结转移准确度均明 显高于CDFI,差异均有统计学意义(均P <0.05),二者联用方案与“金标准”诊 断结果一致性良好(Kappa>0.7)。结论 DWI相较于CDFI能更准确评估甲状腺癌患 者术前颈部淋巴结的转移情况,二者联用 可进一步减少误诊或漏诊,有利于改善手 术安全性。
Objective To explore the clinical value of color Doppler flow imaging (CDFI) and diffusion-weighted imaging (DWI) in the preoperative diagnosis of thyroid cancer. Methods The clinical data of 30 patients with thyroid cancer were analyzed retrospectively. The results of histological examination of intraoperative lymph node dissection pathological specimen were taken as gold standard to analyze the diagnostic efficacy of preoperative CDFI, DWI and their combination in cervical lymph node metastasis. Results The accuracies of DWI and the two combination in diagnosing lymph node metastasis in central area and lateral neck area were significantly higher than those of CDFI (all P<0.05). The combination of the two methods had good consistency with the diagnostic results of gold standard (Kappa>0.7). Conclusion Compared with CDFI, DWI can assess the preoperative cervical lymph node metastasis in patients of thyroid cancer with high accuracy. The combination of the two can reduce the rate of misdiagnosis or missed diagnosis, and it is helpful to improve the safety of surgery.
【关键词】彩超;弥散加权成像;甲状腺 癌;术前;淋巴结转移
【中图分类号】R736.1;R730.4
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.06.012
前言
术中仅凭肉眼区分颈部转移性淋巴结、甲状旁腺及脂肪组织十分 困难[1],而颈部转移性淋巴结的清扫遗漏或过度清扫又可对患者的预 后产生诸多不良影响,因此术前明确淋巴结的转移部位、数目、范围 尤为关键。彩色多普勒超声血流显像(CDFI)在乳腺癌腋窝淋巴结转移 诊断方面已积累了较多的诊断经验[2],而弥散加权成像(DWI)作为磁共 振成像(MRI)常用序列,也在恶性肿瘤淋巴结转移的诊断方面也有较高 的诊断意义[3]。基于此,本研究旨在分析CDFI与DWI独立应用及联合应 用于甲状腺癌淋巴结转移的术前诊断,现将取得成果报道如下。
中国CT和MRI杂志
第17卷, 第 6 期
2019年06月
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