简体中文

论著-头颈部

肝细胞癌患者CT表现及对病理分级的诊断价值

作者:刘志强

所属单位:焦作煤业(集团)有限责任公司中央 医院影像科 (河南 焦作 454150)

PDF

摘要

目的探讨肝细胞癌患者CT表现 及对病理分级的诊断价值。方法 选取 2016年9月至2017年9月在我院诊治的肝 细胞癌并进行部分肝切除术患者500例, 术前进行CT增强扫描,观察CT扫描供血 分型及CT征象中肿瘤大小、门静脉或肝 静脉癌栓、肿瘤内坏死、肝硬化、淋巴 结肿大等情况,并将CT检查结果与术后 病理结果进行对比,分析CT检查结果与 病理分级关系。结果 本研究500例肝细 胞癌患者,肝细胞癌患供血分型为:肝 动脉型317例(63.40%)、肝动脉和门静脉 双重供血型126例(25.20%)、少血供型57 例(11.40%)、门静脉供血型0例。CT扫描 肿瘤大小、门静脉或肝静脉癌栓,与手 术病理结果比较,差异无统计学意义(P >0.05);CT扫描肿瘤内坏死、肝硬化、 淋巴结肿大,与手术病理结果比较,差 异有统计学意义(P<0.05)。病理分级 Ⅰ、Ⅱ级70例(62.50%),Ⅲ、Ⅳ级42例 (37.50%),其中CT显示肿瘤范围越大、边 缘清楚、有肿瘤内出血坏死、有侵袭转移 者,肿瘤分级均较高,差异有统计学意义 (P<0.05)。结论 肝细胞癌患者CT表现能 为病理分级提供客观参考依据,有一定的 诊断价值。

Objective To explore the CT findings and their diagnostic value of pathological grading in patients with hepatocellular carcinoma. Methods A total of 500 cases of patients who diagnosed as hepatocellular carcinoma and treated with partial hepatectomy in our hospital from September 2016 to September 2017 were selected, and they were given CT enhanced scan before operation. The blood supply types of CT scan and the CT signs of tumor size, portal vein or hepatic vein tumor thrombus, necrosis in the tumor, liver cirrhosis and lymphadenopathy were observed. The CT findings were compared with postoperative pathological results, and the relationship between CT findings and pathological grading was analyzed. Results Among 500 patients with hepatocellular carcinoma in this study, 317 cases (63.40%) were hepatic artery type, 126 cases (25.20%) were dual blood supply type of hepatic artery and portal vein, and 57 cases (11.40%) were less blood supply type and 0 case was portal vein blood supply. There were no statistically significant differences in tumor size, portal vein or hepatic vein tumor embolus of CT scan compared with those of surgical pathology results (P>0.05). There were statistical significant differences in the necrosis in the tumor, liver cirrhosis and lymphadenopathy of CT scan compared with those of surgical pathology results (P<0.05). There were 70 cases (62.50%) in pathological grades I and II and 42 cases (37.50%) in grades III and IV. CT showed that the larger cancer cells, the clearer edges, hemorrhage and necrosis in the tumor, and invasion and metastasis all resulted in a higher tumor grade (P<0.05). Conclusion CT findings of patients with hepatocellular carcinoma can provide an objective reference for pathological grading, and it has a certain diagnostic value.

【关键词】肝细胞癌;CT;病例分级

【中图分类号】R735;R814

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.12.028

前言

肝细胞癌是一种全球范围内的恶性肿瘤,主要是乙肝及丙肝病毒 感染,在我国发病率仅次于肺癌和胃癌,而死亡率则仅次于肺癌,且 呈逐年上升趋势,据不完全调查研究统计,我国每年因肝细胞癌死亡 每月在25万~100万之间[1]。肝细胞癌发病早期症状不明显,但病情发 展迅速,预后较差,目前对肝细胞癌诊断主要依靠影像学资料和病理 活检,病理检查能观察肿瘤细胞形态学特征,评估恶性程度,而影像 学检查能明确病变部位、范围、与邻近组织结构的解剖关系,及近、 远处转移情况,在术后随访肿瘤复发和转移上具有检查方便、无创的 优势,病理检查无法比拟[2-5]。本文主要探讨肝细胞癌患者CT表现,及 CT检查对病理分级的诊断价值,现将研究结果报道如下。