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WHOI、II级脑膜瘤 MR表现对比研究及 病理类型分析

作者:童鹏飞 张忠林 易晓敏 梁长虹

所属单位:广东省人民医院放射科 (广东 广州 510080)

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摘要

目的 对比分析WHOⅡ级脑膜瘤和 WHOI级脑膜瘤的影像征象,更好地对两者 进行鉴别诊断。方法 收集本院经手术治 疗的137例WHO I级脑膜瘤与32例WHOⅡ级 脑膜瘤的影像、病理资料,对两种不同级 别脑膜瘤的病理类型及影像征象(形态、 肿瘤有无囊变、平扫信号均匀性、强化均 匀性、瘤周水肿程度、瘤脑界面、脑膜尾 征、邻近颅骨改变等)进行回顾性分析。 结果 169例脑膜瘤中WHOⅠ级脑膜瘤137 例,WHOⅡ级脑膜瘤32例,本组WHO II级 脑膜瘤与WHO I级脑膜瘤相比,分叶状、 肿瘤囊变、平扫信号不均、强化不均匀 程度、瘤周水肿程度、瘤脑界面模糊6项 MR征象差异有统计学意义(P<0.05);邻近 颅骨改变、脑膜尾征差异无统计学意义 (P>0.05)。结论 WHOⅡ级脑膜瘤与WHO I 级脑膜瘤在肿瘤分叶、囊变、平扫信号均 匀性、瘤周水肿、瘤脑界面、强化均匀程 度方面存在差异,有助于鉴别这两种级别 脑膜瘤。

Objective To analyze imaging features of WHO grade I, II meningiomas for a better differential diagnosis. Methods The pathological and imaging data of 137 cases of grade I meningioma and 32 cases of grade II meningioma which were treatable by surgery were studied in terms of pathological types and MRI features such as lobulated sign, necrosis and cystic change, homogenous signal intensity, homogenous enhancement, peritumoral edema, brain tumor interface, dural tail sign and adjacent bone change. Results In 169 intracranialmeningiomas, there are 137 gradeⅠmeningiomas and 32WHO gradeII meningiomas. Differences in lobulated sign, necrosis and cystic change, heterogeneous enhancement and heterogeneous signal intensity, peritumoral edema, brain tumor interface, between WHO grade I meningioma and WH0 grade II meningioma were statistically significant(P<0.05), dural tail sign and adjacent bone change were not statistically significant(P>0.05). Conclusion The MRI features such as lobulated sign, necrosis and cystic change, peritumoral edema, brain tumor interface, homogenous signal intensity and homogenous enhancement are helpful in differential diagnosis of WHO grade I meningioma and WH0 grade II meningioma.

【关键词】WHO I、II级脑膜瘤;磁共振 成像;病理学;鉴别诊断

【中图分类号】R445.2; R739.41

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2017.08.008

前言

脑膜瘤是中枢神经系统最常见的脑外肿瘤,2007版WHO中枢神经系 统肿瘤分型将脑膜瘤分为3级,15个病理亚型,其中Ⅰ级为良性,生长 缓慢,手术切除后不易复发;Ⅱ级生物学行为具有潜在恶性,复发风 险高。两者的预后及治疗方法的选择明显不同[1]。术前通过影像学征 象分析正确鉴别,将有助于手术方法和辅助治疗计划的选择,进而改 善患者预后。Ⅱ级中以非典型性脑膜瘤最多见,其影像学表现多样, 使 II级与部分Ⅰ级脑膜瘤影像学表现存在重叠[2],有时鉴别困难。本 文收集经病理证实的WHOI、Ⅱ级脑膜瘤共169例,分析其病理类型及MR 表现,提高对I、Ⅱ级脑膜瘤的影像鉴别诊断水平。