目的 探究飞利浦Intera 1.5T MR多序列对前列腺增生与前列腺癌的诊断 价值，筛选最佳序列组合应用于临床。方 法 对收集的187例前列腺增生患者、86例 前列腺癌患者行飞利浦Intera 1.5T MR检 查。选用序列有常规序列(T1WI/T2WI)、 脂肪抑制(SPAIR)、弥散成像(DWI)、单 体素波谱成像(MRS)，52例前列腺癌加扫 全身弥散成像(WB-DWI)。对比分析常规序 列、常规序列+SPAIR、常规序列+DWI、常 规序列+SPAIR+DWI、常规序列+DWI+MRS的 应用价值以及WB-DWI对前列腺癌骨转移 的筛查价值。结果 BPH组：常规序列、 常规序列+SPAIR、常规序列+SPAIR+DWI 诊断准确率高(100%)。PCa组：常规序列 +SPAIR+DWI、常规序列+DWI+MRS 诊断准 确率分别为94%和95%，高于其他序列组 合。WB-DWI对前列腺癌骨转移检出率高。 结论 常规序列能够诊断前列腺增生，常 规序列+DWI+MRS对前列腺癌诊断准确率更 高，WB-DWI是无辐射污染、重复性好、检 查步骤不繁琐、一站式筛查全身转移病变 的最好序列。

Objective To Investigate the value of Philips Intera 1.5T MR multiple sequences in diagnosis of benign prostatic hyperplasia(BPH) and prostate cancer(PCa), search the best sequence combination for clinical application. Methods Collected 187 cases of benign prostatic hyperplasia(BPH group), 86 cases of prostate cancer(PCa group), all cases undertake Philips Intera 1.5T MR scan. Scan sequence: conventional sequences(T1WI/T2WI), spectral presaturation attenuated inversion recovery (SPAIR), diffusion weighted imaging(DWI), MR-spectroscopy(MRS).52 cases of PCa add whole body diffusion weighted imaging scan(WB-DWI). Compared and analyzed the application value of conventional sequences, conventional sequences+SPAIR, conventional sequences+DWI, conventional sequences+SPAIR+DWI, conventional sequences+DWI+MRS and the detective value of WB-DWI in bone metastasis of prostate cancer. Results BPH group: Conventional sequences, conventional sequences+ SPAIR, conventional sequences+SPAIR+DWI, the three scanning modes have the highest diagnostic accuracy(100%). PCa group: the diagnostic accuracy rate of conventional sequences+SPAIR+DWI(94%) and conventional sequences+DWI+MRS(95%) are higher than other sequences. WB-DWI has high detection rate in bone metastasis of prostate cancer. Conclusion Conventional sequence can diagnose BPH; conventional sequence+DWI+MRS has higher diagnostic accuracy rate in PCa; WB-DWI is the best sequence in detective bone metastasis of prostate cancer with advantages of no radiation pollution, better repeatability and one-stop body screening.